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Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice.
Tolani B, Celli A, Yao Y, Tan YZ, Fetter R, Liem CR, de Smith AJ, Vasanthakumar T, Bisignano P, Cotton AD, Seiple IB, Rubinstein JL, Jost M, Weissman JS. Tolani B, et al. Among authors: weissman js. Nat Biotechnol. 2022 Dec;40(12):1834-1844. doi: 10.1038/s41587-022-01386-z. Epub 2022 Jul 25. Nat Biotechnol. 2022. PMID: 35879364 Free PMC article.
CRISPR Approaches to Small Molecule Target Identification.
Jost M, Weissman JS. Jost M, et al. Among authors: weissman js. ACS Chem Biol. 2018 Feb 16;13(2):366-375. doi: 10.1021/acschembio.7b00965. Epub 2018 Jan 25. ACS Chem Biol. 2018. PMID: 29261286 Free PMC article. Review.
Molecular recording of mammalian embryogenesis.
Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. Chan MM, et al. Among authors: weissman js. Nature. 2019 Jun;570(7759):77-82. doi: 10.1038/s41586-019-1184-5. Epub 2019 May 13. Nature. 2019. PMID: 31086336 Free PMC article.
Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes.
Horlbeck MA, Liu SJ, Chang HY, Lim DA, Weissman JS. Horlbeck MA, et al. Among authors: weissman js. Nat Biotechnol. 2020 May;38(5):573-576. doi: 10.1038/s41587-020-0428-0. Epub 2020 Feb 24. Nat Biotechnol. 2020. PMID: 32094656 Free PMC article. No abstract available.
Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent.
Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Jost M, et al. Among authors: weissman js. Mol Cell. 2020 Jul 2;79(1):191-198.e3. doi: 10.1016/j.molcel.2020.06.008. Mol Cell. 2020. PMID: 32619469 Free PMC article.
542 results