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Unraveling the mechanism of cell death induced by chemical fibrils.
Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Julien O, et al. Among authors: weissman js. Nat Chem Biol. 2014 Nov;10(11):969-76. doi: 10.1038/nchembio.1639. Epub 2014 Sep 28. Nat Chem Biol. 2014. PMID: 25262416 Free PMC article.
Small-molecule aggregates inhibit amyloid polymerization.
Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. Feng BY, et al. Nat Chem Biol. 2008 Mar;4(3):197-9. doi: 10.1038/nchembio.65. Epub 2008 Jan 27. Nat Chem Biol. 2008. PMID: 18223646 Free PMC article.
Rapid creation and quantitative monitoring of high coverage shRNA libraries.
Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Bassik MC, et al. Among authors: weissman js. Nat Methods. 2009 Jun;6(6):443-5. doi: 10.1038/nmeth.1330. Epub 2009 May 17. Nat Methods. 2009. PMID: 19448642 Free PMC article.
Orm family proteins mediate sphingolipid homeostasis.
Breslow DK, Collins SR, Bodenmiller B, Aebersold R, Simons K, Shevchenko A, Ejsing CS, Weissman JS. Breslow DK, et al. Among authors: weissman js. Nature. 2010 Feb 25;463(7284):1048-53. doi: 10.1038/nature08787. Nature. 2010. PMID: 20182505 Free PMC article.
Global cellular response to chemotherapy-induced apoptosis.
Wiita AP, Ziv E, Wiita PJ, Urisman A, Julien O, Burlingame AL, Weissman JS, Wells JA. Wiita AP, et al. Among authors: weissman js. Elife. 2013 Oct 29;2:e01236. doi: 10.7554/eLife.01236. Elife. 2013. PMID: 24171104 Free PMC article.
Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.
Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Matheny CJ, et al. Among authors: weissman js. Chem Biol. 2013 Nov 21;20(11):1352-63. doi: 10.1016/j.chembiol.2013.09.014. Epub 2013 Oct 31. Chem Biol. 2013. PMID: 24183972 Free PMC article.
542 results