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Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights.
Gray ER, Brookes JC, Caillat C, Turbé V, Webb BLJ, Granger LA, Miller BS, McCoy LE, El Khattabi M, Verrips CT, Weiss RA, Duffy DM, Weissenhorn W, McKendry RA. Gray ER, et al. Among authors: weiss ra. ACS Infect Dis. 2017 Jul 14;3(7):479-491. doi: 10.1021/acsinfecdis.6b00189. Epub 2017 Jun 26. ACS Infect Dis. 2017. PMID: 28591513 Free article.
Nanobodies that Neutralize HIV.
Weiss RA, Verrips CT. Weiss RA, et al. Vaccines (Basel). 2019 Jul 31;7(3):77. doi: 10.3390/vaccines7030077. Vaccines (Basel). 2019. PMID: 31370301 Free PMC article. Review.
Towards an ultra-rapid smartphone- connected test for infectious diseases.
Turbé V, Gray ER, Lawson VE, Nastouli E, Brookes JC, Weiss RA, Pillay D, Emery VC, Verrips CT, Yatsuda H, Athey D, McKendry RA. Turbé V, et al. Among authors: weiss ra. Sci Rep. 2017 Sep 20;7(1):11971. doi: 10.1038/s41598-017-11887-6. Sci Rep. 2017. PMID: 28931860 Free PMC article.
Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.
McCoy LE, Quigley AF, Strokappe NM, Bulmer-Thomas B, Seaman MS, Mortier D, Rutten L, Chander N, Edwards CJ, Ketteler R, Davis D, Verrips T, Weiss RA. McCoy LE, et al. Among authors: weiss ra. J Exp Med. 2012 Jun 4;209(6):1091-103. doi: 10.1084/jem.20112655. Epub 2012 May 28. J Exp Med. 2012. PMID: 22641382 Free PMC article.
Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1.
McCoy LE, Rutten L, Frampton D, Anderson I, Granger L, Bashford-Rogers R, Dekkers G, Strokappe NM, Seaman MS, Koh W, Grippo V, Kliche A, Verrips T, Kellam P, Fassati A, Weiss RA. McCoy LE, et al. Among authors: weiss ra. PLoS Pathog. 2014 Dec 18;10(12):e1004552. doi: 10.1371/journal.ppat.1004552. eCollection 2014 Dec. PLoS Pathog. 2014. PMID: 25522326 Free PMC article.
Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Zhou T, Chen L, Gorman J, Wang S, Kwon YD, Lin BC, Louder MK, Rawi R, Stancofski ED, Yang Y, Zhang B, Quigley AF, McCoy LE, Rutten L, Verrips T, Weiss RA; VRC Production Program; Doria-Rose NA, Shapiro L, Kwong PD. Zhou T, et al. Among authors: weiss ra. Structure. 2022 Jun 2;30(6):862-875.e4. doi: 10.1016/j.str.2022.03.012. Epub 2022 Apr 11. Structure. 2022. PMID: 35413243 Free PMC article.
A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition.
Lutje Hulsik D, Liu YY, Strokappe NM, Battella S, El Khattabi M, McCoy LE, Sabin C, Hinz A, Hock M, Macheboeuf P, Bonvin AM, Langedijk JP, Davis D, Forsman Quigley A, Aasa-Chapman MM, Seaman MS, Ramos A, Poignard P, Favier A, Simorre JP, Weiss RA, Verrips CT, Weissenhorn W, Rutten L. Lutje Hulsik D, et al. Among authors: weiss ra. PLoS Pathog. 2013 Mar;9(3):e1003202. doi: 10.1371/journal.ppat.1003202. Epub 2013 Mar 7. PLoS Pathog. 2013. PMID: 23505368 Free PMC article.
Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas.
Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP Jr, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Martin L, Acharya P, Zhang B, Kwong PD, Mascola JR, Verrips CT, Strokappe NM, Rutten L, McCoy LE, Weiss RA, Brown CS, Jackson R, Silvestri G, Connors M, Burton DR, Shaw GM, Nussenzweig MC, Bjorkman PJ, Ho DD, Farzan M, Hahn BH. Barbian HJ, et al. Among authors: weiss ra. mBio. 2015 Apr 21;6(2):e00296-15. doi: 10.1128/mBio.00296-15. mBio. 2015. PMID: 25900654 Free PMC article.
603 results