Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity.
Porter EA, Weisblum B, Gellman SH.
Porter EA, et al. Among authors: weisblum b.
J Am Chem Soc. 2005 Aug 17;127(32):11516-29. doi: 10.1021/ja0519785.
J Am Chem Soc. 2005.
PMID: 16089482
Some of these longer beta-peptides showed very good antimicrobial activity, but none was more active than a previously reported beta-peptide [Porter, E. A.; Wang, X.; Lee, H.-S.; Weisblum, B.; Gellman, S. H. Nature 2000, 404, 565]. The extensive literature on alpha- …
Some of these longer beta-peptides showed very good antimicrobial activity, but none was more active than a previously reported beta-peptide …