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The pathophysiology of sepsis and precision-medicine-based immunotherapy.
Giamarellos-Bourboulis EJ, Aschenbrenner AC, Bauer M, Bock C, Calandra T, Gat-Viks I, Kyriazopoulou E, Lupse M, Monneret G, Pickkers P, Schultze JL, van der Poll T, van de Veerdonk FL, Vlaar APJ, Weis S, Wiersinga WJ, Netea MG. Giamarellos-Bourboulis EJ, et al. Among authors: weis s. Nat Immunol. 2024 Jan;25(1):19-28. doi: 10.1038/s41590-023-01660-5. Epub 2024 Jan 2. Nat Immunol. 2024. PMID: 38168953 Review.
Metabolic Adaptation Establishes Disease Tolerance to Sepsis.
Weis S, Carlos AR, Moita MR, Singh S, Blankenhaus B, Cardoso S, Larsen R, Rebelo S, Schäuble S, Del Barrio L, Mithieux G, Rajas F, Lindig S, Bauer M, Soares MP. Weis S, et al. Cell. 2017 Jun 15;169(7):1263-1275.e14. doi: 10.1016/j.cell.2017.05.031. Cell. 2017. PMID: 28622511 Free PMC article.
Labile heme impairs hepatic microcirculation and promotes hepatic injury.
Englert FA, Seidel RA, Galler K, Gouveia Z, Soares MP, Neugebauer U, Clemens MG, Sponholz C, Heinemann SH, Pohnert G, Bauer M, Weis S. Englert FA, et al. Among authors: weis s. Arch Biochem Biophys. 2019 Sep 15;672:108075. doi: 10.1016/j.abb.2019.108075. Epub 2019 Aug 11. Arch Biochem Biophys. 2019. PMID: 31412260
Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Divangahi M, Aaby P, Khader SA, Barreiro LB, Bekkering S, Chavakis T, van Crevel R, Curtis N, DiNardo AR, Dominguez-Andres J, Duivenvoorden R, Fanucchi S, Fayad Z, Fuchs E, Hamon M, Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, Matarese G, van der Meer JWM, Mhlanga M, Moorlag SJCFM, Mulder WJM, Naik S, Novakovic B, O'Neill L, Ochando J, Ozato K, Riksen NP, Sauerwein R, Sherwood ER, Schlitzer A, Schultze JL, Sieweke MH, Benn CS, Stunnenberg H, Sun J, van de Veerdonk FL, Weis S, Williams DL, Xavier R, Netea MG. Divangahi M, et al. Among authors: weis s. Nat Immunol. 2021 Jan;22(1):2-6. doi: 10.1038/s41590-020-00845-6. Nat Immunol. 2021. PMID: 33293712 Free PMC article.
Lysine methyltransferase G9a is an important modulator of trained immunity.
Mourits VP, van Puffelen JH, Novakovic B, Bruno M, Ferreira AV, Arts RJ, Groh L, Crișan TO, Zwaag J, Jentho E, Kox M, Pickkers P, van de Veerdonk FL, Weis S, Oosterwijk E, Vermeulen SH, Netea MG, Joosten LA. Mourits VP, et al. Among authors: weis s. Clin Transl Immunology. 2021 Feb 18;10(2):e1253. doi: 10.1002/cti2.1253. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33708384 Free PMC article.
631 results