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Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern.
Cohen-Dvashi H, Weinstein J, Katz M, Eilon-Ashkenazy M, Mor Y, Shimon A, Achdout H, Tamir H, Israely T, Strobelt R, Shemesh M, Stoler-Barak L, Shulman Z, Paran N, Fleishman SJ, Diskin R. Cohen-Dvashi H, et al. Among authors: weinstein j. iScience. 2022 Oct 21;25(10):105193. doi: 10.1016/j.isci.2022.105193. Epub 2022 Sep 28. iScience. 2022. PMID: 36188189 Free PMC article.
Combined Crystal Structure of a Type I Cohesin: MUTATION AND AFFINITY BINDING STUDIES REVEAL STRUCTURAL DETERMINANTS OF COHESIN-DOCKERIN SPECIFICITIES.
Cameron K, Weinstein JY, Zhivin O, Bule P, Fleishman SJ, Alves VD, Gilbert HJ, Ferreira LM, Fontes CM, Bayer EA, Najmudin S. Cameron K, et al. Among authors: weinstein jy. J Biol Chem. 2015 Jun 26;290(26):16215-25. doi: 10.1074/jbc.M115.653303. Epub 2015 May 1. J Biol Chem. 2015. PMID: 25934389 Free PMC article.
Structure and receptor recognition by the Lassa virus spike complex.
Katz M, Weinstein J, Eilon-Ashkenazy M, Gehring K, Cohen-Dvashi H, Elad N, Fleishman SJ, Diskin R. Katz M, et al. Among authors: weinstein j. Nature. 2022 Mar;603(7899):174-179. doi: 10.1038/s41586-022-04429-2. Epub 2022 Feb 16. Nature. 2022. PMID: 35173332
De novo-designed transmembrane domains tune engineered receptor functions.
Elazar A, Chandler NJ, Davey AS, Weinstein JY, Nguyen JV, Trenker R, Cross RS, Jenkins MR, Call MJ, Call ME, Fleishman SJ. Elazar A, et al. Among authors: weinstein jy. Elife. 2022 May 4;11:e75660. doi: 10.7554/eLife.75660. Elife. 2022. PMID: 35506657 Free PMC article.
Computational design of BclxL inhibitors that target transmembrane domain interactions.
Duart G, Elazar A, Weinstein JY, Gadea-Salom L, Ortiz-Mateu J, Fleishman SJ, Mingarro I, Martinez-Gil L. Duart G, et al. Among authors: weinstein jy. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2219648120. doi: 10.1073/pnas.2219648120. Epub 2023 Mar 7. Proc Natl Acad Sci U S A. 2023. PMID: 36881618 Free PMC article.
Designed active-site library reveals thousands of functional GFP variants.
Weinstein JY, Martí-Gómez C, Lipsh-Sokolik R, Hoch SY, Liebermann D, Nevo R, Weissman H, Petrovich-Kopitman E, Margulies D, Ivankov D, McCandlish DM, Fleishman SJ. Weinstein JY, et al. Nat Commun. 2023 May 20;14(1):2890. doi: 10.1038/s41467-023-38099-z. Nat Commun. 2023. PMID: 37210560 Free PMC article.
1,749 results