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Page 1
Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons.
Vadodaria KC, Ji Y, Skime M, Paquola AC, Nelson T, Hall-Flavin D, Heard KJ, Fredlender C, Deng Y, Elkins J, Dani K, Le AT, Marchetto MC, Weinshilboum R, Gage FH. Vadodaria KC, et al. Among authors: weinshilboum r. Mol Psychiatry. 2019 Jun;24(6):808-818. doi: 10.1038/s41380-019-0377-5. Epub 2019 Mar 22. Mol Psychiatry. 2019. PMID: 30903001 Free PMC article.
Validation of the 17-item Hamilton Depression Rating Scale definition of response for adults with major depressive disorder using equipercentile linking to Clinical Global Impression scale ratings: analysis of Pharmacogenomic Research Network Antidepressant Medication Pharmacogenomic Study (PGRN-AMPS) data.
Bobo WV, Angleró GC, Jenkins G, Hall-Flavin DK, Weinshilboum R, Biernacka JM. Bobo WV, et al. Among authors: weinshilboum r. Hum Psychopharmacol. 2016 May;31(3):185-92. doi: 10.1002/hup.2526. Epub 2016 Mar 21. Hum Psychopharmacol. 2016. PMID: 26999588 Free PMC article.
The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.
Biernacka JM, Sangkuhl K, Jenkins G, Whaley RM, Barman P, Batzler A, Altman RB, Arolt V, Brockmöller J, Chen CH, Domschke K, Hall-Flavin DK, Hong CJ, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou YJ, Mushiroda T, Nonen S, Skime MK, Wang L, Baune BT, Kato M, Liu YL, Praphanphoj V, Stingl JC, Tsai SJ, Kubo M, Klein TE, Weinshilboum R. Biernacka JM, et al. Among authors: weinshilboum r. Transl Psychiatry. 2015 Apr 21;5(4):e553. doi: 10.1038/tp.2015.47. Transl Psychiatry. 2015. PMID: 25897834 Free PMC article.
Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression.
MahmoudianDehkordi S, Ahmed AT, Bhattacharyya S, Han X, Baillie RA, Arnold M, Skime MK, John-Williams LS, Moseley MA, Thompson JW, Louie G, Riva-Posse P, Craighead WE, McDonald W, Krishnan R, Rush AJ, Frye MA, Dunlop BW, Weinshilboum RM, Kaddurah-Daouk R; Mood Disorders Precision Medicine Consortium (MDPMC). MahmoudianDehkordi S, et al. Among authors: weinshilboum rm. Transl Psychiatry. 2021 Mar 2;11(1):153. doi: 10.1038/s41398-020-01097-6. Transl Psychiatry. 2021. PMID: 33654056 Free PMC article.
Treatment outcomes of depression: the pharmacogenomic research network antidepressant medication pharmacogenomic study.
Mrazek DA, Biernacka JM, McAlpine DE, Benitez J, Karpyak VM, Williams MD, Hall-Flavin DK, Netzel PJ, Passov V, Rohland BM, Shinozaki G, Hoberg AA, Snyder KA, Drews MS, Skime MK, Sagen JA, Schaid DJ, Weinshilboum R, Katzelnick DJ. Mrazek DA, et al. Among authors: weinshilboum r. J Clin Psychopharmacol. 2014 Jun;34(3):313-7. doi: 10.1097/JCP.0000000000000099. J Clin Psychopharmacol. 2014. PMID: 24743713 Free PMC article. Clinical Trial.
Multi-Omics Characterization of Early- and Adult-Onset Major Depressive Disorder.
Grant CW, Barreto EF, Kumar R, Kaddurah-Daouk R, Skime M, Mayes T, Carmody T, Biernacka J, Wang L, Weinshilboum R, Trivedi MH, Bobo WV, Croarkin PE, Athreya AP. Grant CW, et al. Among authors: weinshilboum r. J Pers Med. 2022 Mar 6;12(3):412. doi: 10.3390/jpm12030412. J Pers Med. 2022. PMID: 35330412 Free PMC article.
Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism.
Ho MF, Zhang C, Moon I, Wei L, Coombes B, Biernacka J, Skime M, Choi DS, Frye M, Schmidt K, Gliske K, Braughton J, Ngo Q, Skillon C, Seppala M, Oesterle T, Karpyak V, Li H, Weinshilboum R. Ho MF, et al. Among authors: weinshilboum r. Mol Metab. 2022 Sep;63:101534. doi: 10.1016/j.molmet.2022.101534. Epub 2022 Jun 22. Mol Metab. 2022. PMID: 35752286 Free PMC article.
Network science approach elucidates integrative genomic-metabolomic signature of antidepressant response and lifetime history of attempted suicide in adults with major depressive disorder.
Grant CW, Wilton AR, Kaddurah-Daouk R, Skime M, Biernacka J, Mayes T, Carmody T, Wang L, Lazaridis K, Weinshilboum R, Bobo WV, Trivedi MH, Croarkin PE, Athreya AP. Grant CW, et al. Among authors: weinshilboum r. Front Pharmacol. 2022 Oct 3;13:984383. doi: 10.3389/fphar.2022.984383. eCollection 2022. Front Pharmacol. 2022. PMID: 36263124 Free PMC article.
541 results