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Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target.
Weingart MF, Roth JJ, Hutt-Cabezas M, Busse TM, Kaur H, Price A, Maynard R, Rubens J, Taylor I, Mao XG, Xu J, Kuwahara Y, Allen SJ, Erdreich-Epstein A, Weissman BE, Orr BA, Eberhart CG, Biegel JA, Raabe EH. Weingart MF, et al. Oncotarget. 2015 Feb 20;6(5):3165-77. doi: 10.18632/oncotarget.3078. Oncotarget. 2015. PMID: 25638158 Free PMC article.
Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes.
Saratsis AM, Kambhampati M, Snyder K, Yadavilli S, Devaney JM, Harmon B, Hall J, Raabe EH, An P, Weingart M, Rood BR, Magge SN, MacDonald TJ, Packer RJ, Nazarian J. Saratsis AM, et al. Acta Neuropathol. 2014;127(6):881-95. doi: 10.1007/s00401-013-1218-2. Epub 2013 Dec 3. Acta Neuropathol. 2014. PMID: 24297113 Free PMC article.
LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase.
Chen D, Cox J, Annam J, Weingart M, Essien G, Rathi KS, Rokita JL, Khurana P, Cuya SM, Bosse KR, Pilgrim A, Li D, Shields C, Laur O, Maris JM, Schnepp RW. Chen D, et al. Neoplasia. 2020 Apr 24;22(6):231-241. doi: 10.1016/j.neo.2020.04.001. Online ahead of print. Neoplasia. 2020. PMID: 32339949 Free PMC article.