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Prodrugs of bisthiazolium salts are orally potent antimalarials.
Vial HJ, Wein S, Farenc C, Kocken C, Nicolas O, Ancelin ML, Bressolle F, Thomas A, Calas M. Vial HJ, et al. Among authors: wein s. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15458-63. doi: 10.1073/pnas.0404037101. Epub 2004 Oct 18. Proc Natl Acad Sci U S A. 2004. PMID: 15492221 Free PMC article.
[Malaria: towards a new treatment!].
Wein S, Calas M, Bressolle F, Herrera S, Thomas A, Vial H. Wein S, et al. Med Sci (Paris). 2005 Apr;21(4):341-3. doi: 10.1051/medsci/2005214341. Med Sci (Paris). 2005. PMID: 15811291 Free article. French. No abstract available.
Mono- and bis-thiazolium salts have potent antimalarial activity.
Hamzé A, Rubi E, Arnal P, Boisbrun M, Carcel C, Salom-Roig X, Maynadier M, Wein S, Vial H, Calas M. Hamzé A, et al. Among authors: wein s. J Med Chem. 2005 May 19;48(10):3639-43. doi: 10.1021/jm0492608. J Med Chem. 2005. PMID: 15887971
Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.
Richier E, Biagini GA, Wein S, Boudou F, Bray PG, Ward SA, Precigout E, Calas M, Dubremetz JF, Vial HJ. Richier E, et al. Among authors: wein s. Antimicrob Agents Chemother. 2006 Oct;50(10):3381-8. doi: 10.1128/AAC.00443-06. Antimicrob Agents Chemother. 2006. PMID: 17005821 Free PMC article.
175 results