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Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Tetreau G, Banneville AS, Andreeva EA, Brewster AS, Hunter MS, Sierra RG, Teulon JM, Young ID, Burke N, Grünewald TA, Beaudouin J, Snigireva I, Fernandez-Luna MT, Burt A, Park HW, Signor L, Bafna JA, Sadir R, Fenel D, Boeri-Erba E, Bacia M, Zala N, Laporte F, Després L, Weik M, Boutet S, Rosenthal M, Coquelle N, Burghammer M, Cascio D, Sawaya MR, Winterhalter M, Gratton E, Gutsche I, Federici B, Pellequer JL, Sauter NK, Colletier JP. Tetreau G, et al. Among authors: weik m. Nat Commun. 2020 Mar 2;11(1):1153. doi: 10.1038/s41467-020-14894-w. Nat Commun. 2020. PMID: 32123169 Free PMC article.
Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography.
Colletier JP, Royant A, Specht A, Sanson B, Nachon F, Masson P, Zaccai G, Sussman JL, Goeldner M, Silman I, Bourgeois D, Weik M. Colletier JP, et al. Among authors: weik m. Acta Crystallogr D Biol Crystallogr. 2007 Nov;63(Pt 11):1115-28. doi: 10.1107/S0907444907044472. Epub 2007 Oct 17. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 18007027
Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis.
Carletti E, Schopfer LM, Colletier JP, Froment MT, Nachon F, Weik M, Lockridge O, Masson P. Carletti E, et al. Among authors: weik m. Chem Res Toxicol. 2011 Jun 20;24(6):797-808. doi: 10.1021/tx100447k. Epub 2011 Apr 18. Chem Res Toxicol. 2011. PMID: 21438623 Free PMC article.
118 results