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Mice expressing activated PI3K rapidly develop advanced colon cancer.
Leystra AA, Deming DA, Zahm CD, Farhoud M, Olson TJ, Hadac JN, Nettekoven LA, Albrecht DM, Clipson L, Sullivan R, Washington MK, Torrealba JR, Weichert JP, Halberg RB. Leystra AA, et al. Among authors: weichert jp. Cancer Res. 2012 Jun 15;72(12):2931-6. doi: 10.1158/0008-5472.CAN-11-4097. Epub 2012 Apr 23. Cancer Res. 2012. PMID: 22525701 Free PMC article.
Small animal micro-CT colonography.
Durkee BY, Weichert JP, Halberg RB. Durkee BY, et al. Among authors: weichert jp. Methods. 2010 Jan;50(1):36-41. doi: 10.1016/j.ymeth.2009.07.008. Epub 2009 Aug 3. Methods. 2010. PMID: 19651214 Free PMC article.
mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers.
Deming DA, Leystra AA, Farhoud M, Nettekoven L, Clipson L, Albrecht D, Washington MK, Sullivan R, Weichert JP, Halberg RB. Deming DA, et al. Among authors: weichert jp. PLoS One. 2013 Apr 9;8(4):e60709. doi: 10.1371/journal.pone.0060709. Print 2013. PLoS One. 2013. PMID: 23593290 Free PMC article.
PIK3CA and APC mutations are synergistic in the development of intestinal cancers.
Deming DA, Leystra AA, Nettekoven L, Sievers C, Miller D, Middlebrooks M, Clipson L, Albrecht D, Bacher J, Washington MK, Weichert J, Halberg RB. Deming DA, et al. Oncogene. 2014 Apr 24;33(17):2245-54. doi: 10.1038/onc.2013.167. Epub 2013 May 27. Oncogene. 2014. PMID: 23708654 Free PMC article.
88 results