Wei W - Search Results

1

USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy.

Xiong W, Gao X, Zhang T, Jiang B, Hu MM, Bu X, Gao Y, Zhang LZ, Xiao BL, He C, Sun Y, Li H, Shi J, Xiao X, Xiang B, Xie C, Chen G, Zhang H, Wei W, Freeman GJ, Shu HB, Wang H, Zhang J. Xiong W, et al. Among authors: wei w. Nat Commun. 2022 Mar 31;13(1):1700. doi: 10.1038/s41467-022-29401-6. Nat Commun. 2022. PMID: 35361799 Free PMC article.

2

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis.

Zhang J, Wan L, Dai X, Sun Y, Wei W. Zhang J, et al. Among authors: wei w. Biochim Biophys Acta. 2014 Apr;1845(2):277-93. doi: 10.1016/j.bbcan.2014.02.001. Epub 2014 Feb 22. Biochim Biophys Acta. 2014. PMID: 24569229 Free PMC article. Review.

3

Targeting Cdc20 as a novel cancer therapeutic strategy.

Wang L, Zhang J, Wan L, Zhou X, Wang Z, Wei W. Wang L, et al. Among authors: wei w. Pharmacol Ther. 2015 Jul;151:141-51. doi: 10.1016/j.pharmthera.2015.04.002. Epub 2015 Apr 4. Pharmacol Ther. 2015. PMID: 25850036 Free PMC article. Review.

4

Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.

Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W. Zhang J, et al. Among authors: wei w. Mol Cell. 2016 Jun 16;62(6):929-942. doi: 10.1016/j.molcel.2016.04.023. Epub 2016 May 26. Mol Cell. 2016. PMID: 27237051 Free PMC article.

5

Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner.

Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, Malumbres M, Liu J, Zou W, Wei W. Liu J, et al. Among authors: wei w. Cell Discov. 2016 Feb 2;2:15044. doi: 10.1038/celldisc.2015.44. eCollection 2016. Cell Discov. 2016. PMID: 27462441 Free PMC article.

6

"FEM1"nism controls SLBP stability during cell cycle.

Zhang J, Liu J, Wei W. Zhang J, et al. Among authors: wei w. Cell Cycle. 2017 Apr 3;16(7):597-598. doi: 10.1080/15384101.2017.1302226. Cell Cycle. 2017. PMID: 28324668 Free PMC article. No abstract available.

7

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, Wei W. Wang B, et al. Among authors: wei w. Nature. 2017 May 18;545(7654):365-369. doi: 10.1038/nature22344. Epub 2017 May 10. Nature. 2017. PMID: 28489822 Free PMC article.

8

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.

Dai X, Gan W, Li X, Wang S, Zhang W, Huang L, Liu S, Zhong Q, Guo J, Zhang J, Chen T, Shimizu K, Beca F, Blattner M, Vasudevan D, Buckley DL, Qi J, Buser L, Liu P, Inuzuka H, Beck AH, Wang L, Wild PJ, Garraway LA, Rubin MA, Barbieri CE, Wong KK, Muthuswamy SK, Huang J, Chen Y, Bradner JE, Wei W. Dai X, et al. Among authors: wei w. Nat Med. 2017 Sep;23(9):1063-1071. doi: 10.1038/nm.4378. Epub 2017 Aug 14. Nat Med. 2017. PMID: 28805820 Free PMC article.

9

Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.

Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W. Zhang J, et al. Among authors: wei w. Nature. 2018 Jan 4;553(7686):91-95. doi: 10.1038/nature25015. Epub 2017 Nov 16. Nature. 2018. PMID: 29160310 Free PMC article.

10

Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.

Chen M, Wan L, Zhang J, Zhang J, Mendez L, Clohessy JG, Berry K, Victor J, Yin Q, Zhu Y, Wei W, Pandolfi PP. Chen M, et al. Among authors: wei w. Nat Commun. 2018 Jan 15;9(1):159. doi: 10.1038/s41467-017-02272-y. Nat Commun. 2018. PMID: 29335436 Free PMC article.

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