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Page 1
A common mechanism of Sec61 translocon inhibition by small molecules.
Itskanov S, Wang L, Junne T, Sherriff R, Xiao L, Blanchard N, Shi WQ, Forsyth C, Hoepfner D, Spiess M, Park E. Itskanov S, et al. Among authors: shi wq. Nat Chem Biol. 2023 Sep;19(9):1063-1071. doi: 10.1038/s41589-023-01337-y. Epub 2023 May 11. Nat Chem Biol. 2023. PMID: 37169959
Mycolactone causes catastrophic Sec61-dependent loss of the endothelial glycocalyx and basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection.
Hsieh LT, Hall BS, Newcombe J, Mendum TA, Umrania Y, Deery MJ, Shi WQ, Salguero FJ, Simmonds RE. Hsieh LT, et al. Among authors: shi wq. bioRxiv [Preprint]. 2023 Feb 21:2023.02.21.529382. doi: 10.1101/2023.02.21.529382. bioRxiv. 2023. PMID: 36865118 Free PMC article. Preprint.
Ring Expansion Leads to a More Potent Analogue of Ipomoeassin F.
Zong G, Hu Z, Duah KB, Andrews LE, Zhou J, O'Keefe S, Whisenhunt L, Shim JS, Du Y, High S, Shi WQ. Zong G, et al. Among authors: shi wq. J Org Chem. 2020 Dec 18;85(24):16226-16235. doi: 10.1021/acs.joc.0c01659. Epub 2020 Dec 2. J Org Chem. 2020. PMID: 33264019 Free PMC article.
25 results