Wei H - Search Results

1

Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4.

Chen X, Li H, Lin Q, Dai S, Qu L, Guo M, Zhang L, Liao J, Wei H, Xu G, Jiang L, Chen Y. Chen X, et al. Among authors: wei h. Eur J Med Chem. 2024 Mar 15;268:116281. doi: 10.1016/j.ejmech.2024.116281. Epub 2024 Feb 28. Eur J Med Chem. 2024. PMID: 38432058

2

Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors.

Qu L, Chen X, Wei H, Guo M, Dai S, Jiang L, Li J, Yue S, Chen Z, Chen Y. Qu L, et al. Among authors: wei h. Commun Chem. 2022 Jan 11;5(1):5. doi: 10.1038/s42004-021-00623-x. Commun Chem. 2022. PMID: 36697561 Free PMC article.

3

Structure-based design of a dual-warhead covalent inhibitor of FGFR4.

Chen X, Li H, Lin Q, Dai S, Yue S, Qu L, Li M, Guo M, Wei H, Li J, Jiang L, Xu G, Chen Y. Chen X, et al. Among authors: wei h. Commun Chem. 2022 Mar 17;5(1):36. doi: 10.1038/s42004-022-00657-9. Commun Chem. 2022. PMID: 36697897 Free PMC article.

4

Characterization of the cholangiocarcinoma drug pemigatinib against FGFR gatekeeper mutants.

Lin Q, Chen X, Qu L, Guo M, Wei H, Dai S, Jiang L, Chen Y. Lin Q, et al. Among authors: wei h. Commun Chem. 2022 Aug 22;5(1):100. doi: 10.1038/s42004-022-00718-z. Commun Chem. 2022. PMID: 36698015 Free PMC article.

5

Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements.

Jiang L, Dai S, Li J, Liang X, Qu L, Chen X, Guo M, Chen Z, Chen L, Wei H, Chen Y. Jiang L, et al. Among authors: wei h. J Biol Chem. 2019 Dec 20;294(51):19795-19803. doi: 10.1074/jbc.RA119.010730. Epub 2019 Nov 13. J Biol Chem. 2019. PMID: 31723028 Free PMC article.

6

Structural basis of tropifexor as a potent and selective agonist of farnesoid X receptor.

Jiang L, Xiao D, Li Y, Dai S, Qu L, Chen X, Guo M, Wei H, Chen Y. Jiang L, et al. Among authors: wei h. Biochem Biophys Res Commun. 2021 Jan 1;534:1047-1052. doi: 10.1016/j.bbrc.2020.10.039. Epub 2020 Oct 26. Biochem Biophys Res Commun. 2021. PMID: 33121679

7

Targeting MCL-1 in cancer: current status and perspectives.

Wang H, Guo M, Wei H, Chen Y. Wang H, et al. Among authors: wei h. J Hematol Oncol. 2021 Apr 21;14(1):67. doi: 10.1186/s13045-021-01079-1. J Hematol Oncol. 2021. PMID: 33883020 Free PMC article. Review.

8

Structural study of ponatinib in inhibiting SRC kinase.

Guo M, Duan Y, Dai S, Li J, Chen X, Qu L, Chen Z, Wei H, Jiang L, Chen Y. Guo M, et al. Among authors: wei h. Biochem Biophys Res Commun. 2022 Apr 2;598:15-19. doi: 10.1016/j.bbrc.2022.02.001. Epub 2022 Feb 2. Biochem Biophys Res Commun. 2022. PMID: 35151199

9

Characterization of the modification of Kelch-like ECH-associated protein 1 by different fumarates.

Qu L, Guo M, Zhang H, Chen X, Wei H, Jiang L, Li J, Chen Z, Dai S, Chen Y. Qu L, et al. Among authors: wei h. Biochem Biophys Res Commun. 2022 May 21;605:9-15. doi: 10.1016/j.bbrc.2022.03.059. Epub 2022 Mar 12. Biochem Biophys Res Commun. 2022. PMID: 35306364

10

Structural insight into the ligand binding mechanism of aryl hydrocarbon receptor.

Dai S, Qu L, Li J, Zhang Y, Jiang L, Wei H, Guo M, Chen X, Chen Y. Dai S, et al. Among authors: wei h. Nat Commun. 2022 Oct 20;13(1):6234. doi: 10.1038/s41467-022-33858-w. Nat Commun. 2022. PMID: 36266304 Free PMC article.

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