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PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB.
Wei H, Wang B, Miyagi M, She Y, Gopalan B, Huang DB, Ghosh G, Stark GR, Lu T. Wei H, et al. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13516-21. doi: 10.1073/pnas.1311784110. Epub 2013 Jul 31. Proc Natl Acad Sci U S A. 2013. PMID: 23904475 Free PMC article.
Role of lysine methylation of NF-κB in differential gene regulation.
Lu T, Yang M, Huang DB, Wei H, Ozer GH, Ghosh G, Stark GR. Lu T, et al. Among authors: wei h. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13510-5. doi: 10.1073/pnas.1311770110. Epub 2013 Jul 31. Proc Natl Acad Sci U S A. 2013. PMID: 23904479 Free PMC article.
Targeting microenvironment in cancer therapeutics.
Martin M, Wei H, Lu T. Martin M, et al. Among authors: wei h. Oncotarget. 2016 Aug 9;7(32):52575-52583. doi: 10.18632/oncotarget.9824. Oncotarget. 2016. PMID: 27270649 Free PMC article. Review.
Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.
Prabhu L, Wei H, Chen L, Demir Ö, Sandusky G, Sun E, Wang J, Mo J, Zeng L, Fishel M, Safa A, Amaro R, Korc M, Zhang ZY, Lu T. Prabhu L, et al. Among authors: wei h. Oncotarget. 2017 Jun 20;8(25):39963-39977. doi: 10.18632/oncotarget.18102. Oncotarget. 2017. PMID: 28591716 Free PMC article.
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