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A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.
Hayek SS, Koh KH, Grams ME, Wei C, Ko YA, Li J, Samelko B, Lee H, Dande RR, Lee HW, Hahm E, Peev V, Tracy M, Tardi NJ, Gupta V, Altintas MM, Garborcauskas G, Stojanovic N, Winkler CA, Lipkowitz MS, Tin A, Inker LA, Levey AS, Zeier M, Freedman BI, Kopp JB, Skorecki K, Coresh J, Quyyumi AA, Sever S, Reiser J. Hayek SS, et al. Among authors: wei c. Nat Med. 2017 Aug;23(8):945-953. doi: 10.1038/nm.4362. Epub 2017 Jun 26. Nat Med. 2017. PMID: 28650456 Free PMC article.
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.
Reiser J, Polu KR, Möller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR. Reiser J, et al. Among authors: wei c. Nat Genet. 2005 Jul;37(7):739-44. doi: 10.1038/ng1592. Epub 2005 May 27. Nat Genet. 2005. PMID: 15924139 Free PMC article.
Induction of TRPC6 channel in acquired forms of proteinuric kidney disease.
Möller CC, Wei C, Altintas MM, Li J, Greka A, Ohse T, Pippin JW, Rastaldi MP, Wawersik S, Schiavi S, Henger A, Kretzler M, Shankland SJ, Reiser J. Möller CC, et al. Among authors: wei c. J Am Soc Nephrol. 2007 Jan;18(1):29-36. doi: 10.1681/ASN.2006091010. Epub 2006 Dec 13. J Am Soc Nephrol. 2007. PMID: 17167110
Modification of kidney barrier function by the urokinase receptor.
Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J. Wei C, et al. Nat Med. 2008 Jan;14(1):55-63. doi: 10.1038/nm1696. Epub 2007 Dec 16. Nat Med. 2008. PMID: 18084301
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis.
Wei C, El Hindi S, Li J, Fornoni A, Goes N, Sageshima J, Maiguel D, Karumanchi SA, Yap HK, Saleem M, Zhang Q, Nikolic B, Chaudhuri A, Daftarian P, Salido E, Torres A, Salifu M, Sarwal MM, Schaefer F, Morath C, Schwenger V, Zeier M, Gupta V, Roth D, Rastaldi MP, Burke G, Ruiz P, Reiser J. Wei C, et al. Nat Med. 2011 Jul 31;17(8):952-60. doi: 10.1038/nm.2411. Nat Med. 2011. PMID: 21804539 Free PMC article.
Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease.
Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, Ley K, Reiser J, Gupta V. Maiguel D, et al. Among authors: wei c. Sci Signal. 2011 Sep 6;4(189):ra57. doi: 10.1126/scisignal.2001811. Sci Signal. 2011. PMID: 21900205 Free PMC article.
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival.
Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, Reinheckel T, Gu C, Huber TB, Ju W, Bitzer M, Rastaldi MP, Ruiz P, Tryggvason K, Shaw AS, Faul C, Sever S, Reiser J. Yaddanapudi S, et al. Among authors: wei c. J Clin Invest. 2011 Oct;121(10):3965-80. doi: 10.1172/JCI58552. Epub 2011 Sep 12. J Clin Invest. 2011. PMID: 21911934 Free PMC article.
8,460 results