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An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.
Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, Huganir RL, Müller FU, Wehrens XHT, Liu JO, Luczak ED, Bezzerides VJ, Anderson ME. Reyes Gaido OE, et al. Among authors: wehrens xht. Sci Transl Med. 2023 Jun 21;15(701):eabq7839. doi: 10.1126/scitranslmed.abq7839. Epub 2023 Jun 21. Sci Transl Med. 2023. PMID: 37343080 Free PMC article.
Variant-specific therapy for long QT syndrome type 3.
Moore OM, Dorn LE, Wehrens XHT. Moore OM, et al. Among authors: wehrens xht. Heart Rhythm. 2023 May;20(5):718-719. doi: 10.1016/j.hrthm.2023.02.013. Epub 2023 Feb 15. Heart Rhythm. 2023. PMID: 36806575 Free PMC article. No abstract available.
Kinase Inhibitors and Atrial Fibrillation: Mechanisms of Action and Clinical Implications.
Potter AS, Hulsurkar MM, Wu L, Narasimhan B, Karimzad K, Koutroumpakis E, Palaskas N, Deswal A, Kantharia BK, Wehrens XHT. Potter AS, et al. Among authors: wehrens xht. JACC Clin Electrophysiol. 2023 Apr;9(4):591-602. doi: 10.1016/j.jacep.2022.11.034. Epub 2023 Feb 22. JACC Clin Electrophysiol. 2023. PMID: 37100538 Free article. Review.
Long-term efficacy and safety of cardiac genome editing for catecholaminergic polymorphic ventricular tachycardia.
Moore OM, Aguilar-Sanchez Y, Lahiri SK, Hulsurkar MM, Alberto Navarro-Garcia J, Word TA, Keefe JA, Barazi D, Munivez EM, Moore CT, Parthasarathy V, Davidson J, Lagor WR, Park SH, Bao G, Miyake CY, Wehrens XHT. Moore OM, et al. Among authors: wehrens xht. J Cardiovasc Aging. 2024 Jan;4(1):8. doi: 10.20517/jca.2023.42. Epub 2024 Jan 4. J Cardiovasc Aging. 2024. PMID: 38464671
Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads.
Lee CS, Jung SY, Yee RSZ, Agha NH, Hong J, Chang T, Babcock LW, Fleischman JD, Clayton B, Hanna AD, Ward CS, Lanza D, Hurley AE, Zhang P, Wehrens XHT, Lagor WR, Rodney GG, Hamilton SL. Lee CS, et al. Among authors: wehrens xht. Commun Biol. 2023 Sep 14;6(1):942. doi: 10.1038/s42003-023-05330-y. Commun Biol. 2023. PMID: 37709832 Free PMC article.
246 results