Wehrens XH - Search Results

1

Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy.

Himelman E, Lillo MA, Nouet J, Gonzalez JP, Zhao Q, Xie LH, Li H, Liu T, Wehrens XH, Lampe PD, Fishman GI, Shirokova N, Contreras JE, Fraidenraich D. Himelman E, et al. Among authors: wehrens xh. J Clin Invest. 2020 Apr 1;130(4):1713-1727. doi: 10.1172/JCI128190. J Clin Invest. 2020. PMID: 31910160 Free PMC article.

2

Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.

Chelu MG, Sarma S, Sood S, Wang S, van Oort RJ, Skapura DG, Li N, Santonastasi M, Müller FU, Schmitz W, Schotten U, Anderson ME, Valderrábano M, Dobrev D, Wehrens XH. Chelu MG, et al. Among authors: wehrens xh. J Clin Invest. 2009 Jul;119(7):1940-51. doi: 10.1172/jci37059. J Clin Invest. 2009. PMID: 19603549 Free PMC article.

3

PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1.

Wang GS, Kuyumcu-Martinez MN, Sarma S, Mathur N, Wehrens XH, Cooper TA. Wang GS, et al. Among authors: wehrens xh. J Clin Invest. 2009 Dec;119(12):3797-806. doi: 10.1172/JCI37976. Epub 2009 Nov 9. J Clin Invest. 2009. PMID: 19907076 Free PMC article.

4

Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy.

Sarma S, Li N, van Oort RJ, Reynolds C, Skapura DG, Wehrens XH. Sarma S, et al. Among authors: wehrens xh. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13165-70. doi: 10.1073/pnas.1004509107. Epub 2010 Jul 6. Proc Natl Acad Sci U S A. 2010. PMID: 20615971 Free PMC article.

5

Inhibition of CaMKII phosphorylation of RyR2 prevents inducible ventricular arrhythmias in mice with Duchenne muscular dystrophy.

Ather S, Wang W, Wang Q, Li N, Anderson ME, Wehrens XH. Ather S, et al. Among authors: wehrens xh. Heart Rhythm. 2013 Apr;10(4):592-9. doi: 10.1016/j.hrthm.2012.12.016. Epub 2012 Dec 12. Heart Rhythm. 2013. PMID: 23246599 Free PMC article.

6

Oxidative stress and ca(2+) release events in mouse cardiomyocytes.

Shirokova N, Kang C, Fernandez-Tenorio M, Wang W, Wang Q, Wehrens XHT, Niggli E. Shirokova N, et al. Biophys J. 2014 Dec 16;107(12):2815-2827. doi: 10.1016/j.bpj.2014.10.054. Biophys J. 2014. PMID: 25517148 Free PMC article. Retracted.

7

Crosstalk between RyR2 oxidation and phosphorylation contributes to cardiac dysfunction in mice with Duchenne muscular dystrophy.

Wang Q, Wang W, Wang G, Rodney GG, Wehrens XH. Wang Q, et al. Among authors: wehrens xh. J Mol Cell Cardiol. 2015 Dec;89(Pt B):177-84. doi: 10.1016/j.yjmcc.2015.11.009. Epub 2015 Nov 7. J Mol Cell Cardiol. 2015. PMID: 26555638 Free PMC article.

8

Oxidized CaMKII (Ca²⁺/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy.

Wang Q, Quick AP, Cao S, Reynolds J, Chiang DY, Beavers D, Li N, Wang G, Rodney GG, Anderson ME, Wehrens XHT. Wang Q, et al. Circ Arrhythm Electrophysiol. 2018 Apr;11(4):e005682. doi: 10.1161/CIRCEP.117.005682. Circ Arrhythm Electrophysiol. 2018. PMID: 29654126 Free PMC article.

9

STAT3: a link between CaMKII-βIV-spectrin and maladaptive remodeling?

Hulsurkar M, Quick AP, Wehrens XH. Hulsurkar M, et al. Among authors: wehrens xh. J Clin Invest. 2018 Dec 3;128(12):5219-5221. doi: 10.1172/JCI124778. Epub 2018 Nov 12. J Clin Invest. 2018. PMID: 30418170 Free PMC article.

10

Oxidized CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms.

Mesubi OO, Rokita AG, Abrol N, Wu Y, Chen B, Wang Q, Granger JM, Tucker-Bartley A, Luczak ED, Murphy KR, Umapathi P, Banerjee PS, Boronina TN, Cole RN, Maier LS, Wehrens XH, Pomerantz JL, Song LS, Ahima RS, Hart GW, Zachara NE, Anderson ME. Mesubi OO, et al. Among authors: wehrens xh. J Clin Invest. 2021 Jan 19;131(2):e95747. doi: 10.1172/JCI95747. J Clin Invest. 2021. PMID: 33151911 Free PMC article.

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