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Non-Fibrillar Oligomeric Amyloid-β within Synapses.
Pickett EK, Koffie RM, Wegmann S, Henstridge CM, Herrmann AG, Colom-Cadena M, Lleo A, Kay KR, Vaught M, Soberman R, Walsh DM, Hyman BT, Spires-Jones TL. Pickett EK, et al. Among authors: wegmann s. J Alzheimers Dis. 2016 May 30;53(3):787-800. doi: 10.3233/JAD-160007. J Alzheimers Dis. 2016. PMID: 27258414
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
Pooler AM, Polydoro M, Maury EA, Nicholls SB, Reddy SM, Wegmann S, William C, Saqran L, Cagsal-Getkin O, Pitstick R, Beier DR, Carlson GA, Spires-Jones TL, Hyman BT. Pooler AM, et al. Among authors: wegmann s. Acta Neuropathol Commun. 2015 Mar 24;3:14. doi: 10.1186/s40478-015-0199-x. Acta Neuropathol Commun. 2015. PMID: 25853174 Free PMC article.
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.
Wegmann S, Maury EA, Kirk MJ, Saqran L, Roe A, DeVos SL, Nicholls S, Fan Z, Takeda S, Cagsal-Getkin O, William CM, Spires-Jones TL, Pitstick R, Carlson GA, Pooler AM, Hyman BT. Wegmann S, et al. EMBO J. 2015 Dec 14;34(24):3028-41. doi: 10.15252/embj.201592748. Epub 2015 Nov 4. EMBO J. 2015. PMID: 26538322 Free PMC article.
85 results