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Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Sandusky-Beltran LA, Kovalenko A, Ma C, Calahatian JIT, Placides DS, Watler MD, Hunt JB, Darling AL, Baker JD, Blair LJ, Martin MD, Fontaine SN, Dickey CA, Lussier AL, Weeber EJ, Selenica MB, Nash KR, Gordon MN, Morgan D, Lee DC. Sandusky-Beltran LA, et al. Among authors: weeber ej. Alzheimers Res Ther. 2019 Jun 29;11(1):58. doi: 10.1186/s13195-019-0507-y. Alzheimers Res Ther. 2019. PMID: 31253191 Free PMC article.
Chemical manipulation of hsp70 ATPase activity regulates tau stability.
Jinwal UK, Miyata Y, Koren J 3rd, Jones JR, Trotter JH, Chang L, O'Leary J, Morgan D, Lee DC, Shults CL, Rousaki A, Weeber EJ, Zuiderweg ER, Gestwicki JE, Dickey CA. Jinwal UK, et al. Among authors: weeber ej. J Neurosci. 2009 Sep 30;29(39):12079-88. doi: 10.1523/JNEUROSCI.3345-09.2009. J Neurosci. 2009. PMID: 19793966 Free PMC article.
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden.
O'Leary JC 3rd, Li Q, Marinec P, Blair LJ, Congdon EE, Johnson AG, Jinwal UK, Koren J 3rd, Jones JR, Kraft C, Peters M, Abisambra JF, Duff KE, Weeber EJ, Gestwicki JE, Dickey CA. O'Leary JC 3rd, et al. Among authors: weeber ej. Mol Neurodegener. 2010 Nov 1;5:45. doi: 10.1186/1750-1326-5-45. Mol Neurodegener. 2010. PMID: 21040568 Free PMC article.
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.
Abisambra JF, Blair LJ, Hill SE, Jones JR, Kraft C, Rogers J, Koren J 3rd, Jinwal UK, Lawson L, Johnson AG, Wilcock D, O'Leary JC, Jansen-West K, Muschol M, Golde TE, Weeber EJ, Banko J, Dickey CA. Abisambra JF, et al. Among authors: weeber ej. J Neurosci. 2010 Nov 17;30(46):15374-82. doi: 10.1523/JNEUROSCI.3155-10.2010. J Neurosci. 2010. PMID: 21084594 Free PMC article.
The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics.
Jinwal UK, Trotter JH, Abisambra JF, Koren J 3rd, Lawson LY, Vestal GD, O'Leary JC 3rd, Johnson AG, Jin Y, Jones JR, Li Q, Weeber EJ, Dickey CA. Jinwal UK, et al. Among authors: weeber ej. J Biol Chem. 2011 May 13;286(19):16976-83. doi: 10.1074/jbc.M110.182493. Epub 2011 Mar 2. J Biol Chem. 2011. PMID: 21367866 Free PMC article.
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.
O'Leary JC 3rd, Dharia S, Blair LJ, Brady S, Johnson AG, Peters M, Cheung-Flynn J, Cox MB, de Erausquin G, Weeber EJ, Jinwal UK, Dickey CA. O'Leary JC 3rd, et al. Among authors: weeber ej. PLoS One. 2011;6(9):e24840. doi: 10.1371/journal.pone.0024840. Epub 2011 Sep 15. PLoS One. 2011. PMID: 21935478 Free PMC article.
ApoER2 function in the establishment and maintenance of retinal synaptic connectivity.
Trotter JH, Klein M, Jinwal UK, Abisambra JF, Dickey CA, Tharkur J, Masiulis I, Ding J, Locke KG, Rickman CB, Birch DG, Weeber EJ, Herz J. Trotter JH, et al. Among authors: weeber ej. J Neurosci. 2011 Oct 5;31(40):14413-23. doi: 10.1523/JNEUROSCI.3135-11.2011. J Neurosci. 2011. PMID: 21976526 Free PMC article.
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau.
Abisambra J, Jinwal UK, Miyata Y, Rogers J, Blair L, Li X, Seguin SP, Wang L, Jin Y, Bacon J, Brady S, Cockman M, Guidi C, Zhang J, Koren J, Young ZT, Atkins CA, Zhang B, Lawson LY, Weeber EJ, Brodsky JL, Gestwicki JE, Dickey CA. Abisambra J, et al. Among authors: weeber ej. Biol Psychiatry. 2013 Sep 1;74(5):367-74. doi: 10.1016/j.biopsych.2013.02.027. Epub 2013 Apr 19. Biol Psychiatry. 2013. PMID: 23607970 Free PMC article.
116 results