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HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.
Ombrello MJ, Remmers EF, Tachmazidou I, Grom A, Foell D, Haas JP, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Mellins ED, Ilowite NT, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg A, Wedderburn LR, Anton J, Schwarz T, Hinks A, Bilginer Y, Park J, Cobb J, Satorius CL, Han B, Baskin E, Signa S, Duerr RH, Achkar JP, Kamboh MI, Kaufman KM, Kottyan LC, Pinto D, Scherer SW, Alarcón-Riquelme ME, Docampo E, Estivill X, Gül A; British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group; Childhood Arthritis Prospective Study (CAPS) Group; Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators; Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group; Biologically Based Outcome Predictors in JIA (BBOP) Group; de Bakker PI, Raychaudhuri S, Langefeld CD, Thompson S, Zeggini E, Thomson W, Kastner DL, Woo P; International Childhood Arthritis Genetics (INCHARGE) Consortium. Ombrello MJ, et al. Among authors: wedderburn lr. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15970-5. doi: 10.1073/pnas.1520779112. Epub 2015 Nov 23. Proc Natl Acad Sci U S A. 2015. PMID: 26598658 Free PMC article.
Labeling antigen-specific CD4(+) T cells with class II MHC oligomers.
Cameron TO, Norris PJ, Patel A, Moulon C, Rosenberg ES, Mellins ED, Wedderburn LR, Stern LJ. Cameron TO, et al. Among authors: wedderburn lr. J Immunol Methods. 2002 Oct 1;268(1):51-69. doi: 10.1016/s0022-1759(02)00200-4. J Immunol Methods. 2002. PMID: 12213343 Review.
Autologous T cell depleted haematopoietic stem cell transplantation in children with severe juvenile idiopathic arthritis in the UK (2000-2007).
Abinun M, Flood TJ, Cant AJ, Veys P, Gennery AR, Foster HE, Friswell M, Baildam E, Davidson J, Southwood TR, Livermore P, Wedderburn LR. Abinun M, et al. Among authors: wedderburn lr. Mol Immunol. 2009 Nov;47(1):46-51. doi: 10.1016/j.molimm.2008.12.029. Epub 2009 Feb 8. Mol Immunol. 2009. PMID: 19203795 Clinical Trial.
HLA-DPB1 associations differ between DRB1*03 positive anti-Jo-1 and anti-PM-Scl antibody positive idiopathic inflammatory myopathy.
Chinoy H, Payne D, Poulton KV, Fertig N, Betteridge Z, Gunawardena H, Davidson JE, Oddis CV, McHugh NJ, Wedderburn LR, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration & UK Juvenile Dermatomyositis Research Group. Chinoy H, et al. Among authors: wedderburn lr. Rheumatology (Oxford). 2009 Oct;48(10):1213-7. doi: 10.1093/rheumatology/kep248. Epub 2009 Aug 18. Rheumatology (Oxford). 2009. PMID: 19690132
Disease activity and disability in children with juvenile idiopathic arthritis one year following presentation to paediatric rheumatology. Results from the Childhood Arthritis Prospective Study.
Hyrich KL, Lal SD, Foster HE, Thornton J, Adib N, Baildam E, Gardner-Medwin J, Wedderburn LR, Chieng A, Davidson J, Thomson W. Hyrich KL, et al. Among authors: wedderburn lr. Rheumatology (Oxford). 2010 Jan;49(1):116-22. doi: 10.1093/rheumatology/kep352. Epub 2009 Nov 19. Rheumatology (Oxford). 2010. PMID: 19926670 Free PMC article.
217 results