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Discovery, synthesis and in combo studies of a tetrazole analogue of clofibric acid as a potent hypoglycemic agent.
Navarrete-Vázquez G, Alaniz-Palacios A, Hidalgo-Figueroa S, González-Acevedo C, Ávila-Villarreal G, Estrada-Soto S, Webster SP, Medina-Franco JL, López-Vallejo F, Guerrero-Álvarez J, Tlahuext H. Navarrete-Vázquez G, et al. Among authors: webster sp. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3244-7. doi: 10.1016/j.bmcl.2013.03.122. Epub 2013 Apr 5. Bioorg Med Chem Lett. 2013. PMID: 23597793
Antidiabetic activity of N-(6-substituted-1,3-benzothiazol-2-yl)benzenesulfonamides.
Moreno-Díaz H, Villalobos-Molina R, Ortiz-Andrade R, Díaz-Coutiño D, Medina-Franco JL, Webster SP, Binnie M, Estrada-Soto S, Ibarra-Barajas M, León-Rivera I, Navarrete-Vázquez G. Moreno-Díaz H, et al. Among authors: webster sp. Bioorg Med Chem Lett. 2008 May 1;18(9):2871-7. doi: 10.1016/j.bmcl.2008.03.086. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18424136
A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.
Torres-Piedra M, Ortiz-Andrade R, Villalobos-Molina R, Singh N, Medina-Franco JL, Webster SP, Binnie M, Navarrete-Vázquez G, Estrada-Soto S. Torres-Piedra M, et al. Among authors: webster sp. Eur J Med Chem. 2010 Jun;45(6):2606-12. doi: 10.1016/j.ejmech.2010.02.049. Epub 2010 Mar 1. Eur J Med Chem. 2010. PMID: 20346546
Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities.
Navarrete-Vázquez G, Morales-Vilchis MG, Estrada-Soto S, Ramírez-Espinosa JJ, Hidalgo-Figueroa S, Nava-Zuazo C, Tlahuext H, Leon-Rivera I, Medina-Franco JL, López-Vallejo F, Webster SP, Binnie M, Ortiz-Andrade R, Moreno-Diaz H. Navarrete-Vázquez G, et al. Among authors: webster sp. Eur J Med Chem. 2014 Mar 3;74:179-86. doi: 10.1016/j.ejmech.2013.12.042. Epub 2014 Jan 8. Eur J Med Chem. 2014. PMID: 24462849
Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation.
Ortiz-Andrade RR, Sánchez-Salgado JC, Navarrete-Vázquez G, Webster SP, Binnie M, García-Jiménez S, León-Rivera I, Cigarroa-Vázquez P, Villalobos-Molina R, Estrada-Soto S. Ortiz-Andrade RR, et al. Among authors: webster sp. Diabetes Obes Metab. 2008 Nov;10(11):1097-104. doi: 10.1111/j.1463-1326.2008.00869.x. Epub 2008 Mar 18. Diabetes Obes Metab. 2008. PMID: 18355329
Antihyperglycemic and sub-chronic antidiabetic actions of morolic and moronic acids, in vitro and in silico inhibition of 11β-HSD 1.
Ramírez-Espinosa JJ, García-Jiménez S, Rios MY, Medina-Franco JL, López-Vallejo F, Webster SP, Binnie M, Ibarra-Barajas M, Ortiz-Andrade R, Estrada-Soto S. Ramírez-Espinosa JJ, et al. Among authors: webster sp. Phytomedicine. 2013 May 15;20(7):571-6. doi: 10.1016/j.phymed.2013.01.013. Epub 2013 Feb 27. Phytomedicine. 2013. PMID: 23453304
66 results