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A One Health overview, facilitating advances in comparative medicine and translational research.
Stroud C, Dmitriev I, Kashentseva E, Bryan JN, Curiel DT, Rindt H, Reinero C, Henry CJ, Bergman PJ, Mason NJ, Gnanandarajah JS, Engiles JB, Gray F, Laughlin D, Gaurnier-Hausser A, Wallecha A, Huebner M, Paterson Y, O'Connor D, Treml LS, Stannard JP, Cook JL, Jacobs M, Wyckoff GJ, Likins L, Sabbagh U, Skaff A, Guloy AS, Hays HD, LeBlanc AK, Coates JR, Katz ML, Lyons LA, Johnson GC, Johnson GS, O'Brien DP, Duan D, Calvet JP, Gandolfi B, Baron DA, Weiss ML, Webster DA, Karanu FN, Robb EJ, Harman RJ. Stroud C, et al. Among authors: webster da. Clin Transl Med. 2016 Aug;5(Suppl 1):26. doi: 10.1186/s40169-016-0107-4. Clin Transl Med. 2016. PMID: 27558513 Free PMC article.
First gene-edited calf with reduced susceptibility to a major viral pathogen.
Workman AM, Heaton MP, Vander Ley BL, Webster DA, Sherry L, Bostrom JR, Larson S, Kalbfleisch TS, Harhay GP, Jobman EE, Carlson DF, Sonstegard TS. Workman AM, et al. Among authors: webster da. PNAS Nexus. 2023 May 9;2(5):pgad125. doi: 10.1093/pnasnexus/pgad125. eCollection 2023 May. PNAS Nexus. 2023. PMID: 37181049 Free PMC article.
Author Correction: Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs.
Schneider JW, Oommen S, Qureshi MY, Goetsch SC, Pease DR, Sundsbak RS, Guo W, Sun M, Sun H, Kuroyanagi H, Webster DA, Coutts AW, Holst KA, Edwards BS, Newville N, Hathcock MA, Melkamu T, Briganti F, Wei W, Romanelli MG, Fahrenkrug SC, Frantz DE, Olson TM, Steinmetz LM, Carlson DF, Nelson TJ; Wanek Program Preclinical Pipeline. Schneider JW, et al. Among authors: webster da. Nat Med. 2021 Jul;27(7):1309. doi: 10.1038/s41591-021-01412-8. Nat Med. 2021. PMID: 34079106 No abstract available.
Liver development is restored by blastocyst complementation of HHEX knockout in mice and pigs.
Ruiz-Estevez M, Crane AT, Rodriguez-Villamil P, Ongaratto FL, You Y, Steevens AR, Hill C, Goldsmith T, Webster DA, Sherry L, Lim S, Denman N, Low WC, Carlson DF, Dutton JR, Steer CJ, Gafni O. Ruiz-Estevez M, et al. Among authors: webster da. Stem Cell Res Ther. 2021 May 19;12(1):292. doi: 10.1186/s13287-021-02348-z. Stem Cell Res Ther. 2021. PMID: 34011403 Free PMC article.
Development of a porcine model of phenylketonuria with a humanized R408W mutation for gene editing.
Kaiser RA, Carlson DF, Allen KL, Webster DA, VanLith CJ, Nicolas CT, Hillin LG, Yu Y, Kaiser CW, Wahoff WR, Hickey RD, Watson AL, Winn SR, Thöny B, Kern DR, Harding CO, Lillegard JB. Kaiser RA, et al. Among authors: webster da. PLoS One. 2021 Jan 25;16(1):e0245831. doi: 10.1371/journal.pone.0245831. eCollection 2021. PLoS One. 2021. PMID: 33493163 Free PMC article.
Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs.
Schneider JW, Oommen S, Qureshi MY, Goetsch SC, Pease DR, Sundsbak RS, Guo W, Sun M, Sun H, Kuroyanagi H, Webster DA, Coutts AW, Holst KA, Edwards BS, Newville N, Hathcock MA, Melkamu T, Briganti F, Wei W, Romanelli MG, Fahrenkrug SC, Frantz DE, Olson TM, Steinmetz LM, Carlson DF, Nelson TJ; Wanek Program Preclinical Pipeline. Schneider JW, et al. Among authors: webster da. Nat Med. 2020 Nov;26(11):1788-1800. doi: 10.1038/s41591-020-1087-x. Epub 2020 Nov 13. Nat Med. 2020. PMID: 33188278 Free PMC article.
121 results