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The fungal ligand chitin directly binds TLR2 and triggers inflammation dependent on oligomer size.
Fuchs K, Cardona Gloria Y, Wolz OO, Herster F, Sharma L, Dillen CA, Täumer C, Dickhöfer S, Bittner Z, Dang TM, Singh A, Haischer D, Schlöffel MA, Koymans KJ, Sanmuganantham T, Krach M, Roger T, Le Roy D, Schilling NA, Frauhammer F, Miller LS, Nürnberger T, LeibundGut-Landmann S, Gust AA, Macek B, Frank M, Gouttefangeas C, Dela Cruz CS, Hartl D, Weber AN. Fuchs K, et al. EMBO Rep. 2018 Dec;19(12):e46065. doi: 10.15252/embr.201846065. Epub 2018 Oct 18. EMBO Rep. 2018. PMID: 30337494 Free PMC article.
Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis.
Herster F, Bittner Z, Codrea MC, Archer NK, Heister M, Löffler MW, Heumos S, Wegner J, Businger R, Schindler M, Stegner D, Schäkel K, Grabbe S, Ghoreschi K, Miller LS, Weber ANR. Herster F, et al. Among authors: weber anr. Front Immunol. 2019 Aug 16;10:1867. doi: 10.3389/fimmu.2019.01867. eCollection 2019. Front Immunol. 2019. PMID: 31474979 Free PMC article.
Staphylococcus aureus Skin Colonization Is Enhanced by the Interaction of Neutrophil Extracellular Traps with Keratinocytes.
Bitschar K, Staudenmaier L, Klink L, Focken J, Sauer B, Fehrenbacher B, Herster F, Bittner Z, Bleul L, Schaller M, Wolz C, Weber ANR, Peschel A, Schittek B. Bitschar K, et al. Among authors: weber anr. J Invest Dermatol. 2020 May;140(5):1054-1065.e4. doi: 10.1016/j.jid.2019.10.017. Epub 2019 Dec 17. J Invest Dermatol. 2020. PMID: 31857094 Free article.
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.
Herster F, Bittner Z, Archer NK, Dickhöfer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Löffler MW, Kalbacher H, Vierbuchen T, Heine H, Miller LS, Hartl D, Freund L, Schäkel K, Heister M, Ghoreschi K, Weber ANR. Herster F, et al. Among authors: weber anr. Nat Commun. 2020 Jan 8;11(1):105. doi: 10.1038/s41467-019-13756-4. Nat Commun. 2020. PMID: 31913271 Free PMC article.
Platelets: Underestimated Regulators of Autoinflammation in Psoriasis.
Herster F, Karbach S, Chatterjee M, Weber ANR. Herster F, et al. Among authors: weber anr. J Invest Dermatol. 2021 Jun;141(6):1395-1403. doi: 10.1016/j.jid.2020.12.025. Epub 2021 Mar 31. J Invest Dermatol. 2021. PMID: 33810836 Free article. Review.
80 results