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Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression.
Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, Nasir A, Bjarnadottir O, Werb Z, Kabos P, Chen YY, Hwang ES, Park M, Coussens LM, Nelson AC, Hansen KC, Weaver VM. Maller O, et al. Among authors: weaver vm. Nat Mater. 2021 Apr;20(4):548-559. doi: 10.1038/s41563-020-00849-5. Epub 2020 Nov 30. Nat Mater. 2021. PMID: 33257795 Free PMC article.
Tensional homeostasis and the malignant phenotype.
Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM. Paszek MJ, et al. Among authors: weaver vm. Cancer Cell. 2005 Sep;8(3):241-54. doi: 10.1016/j.ccr.2005.08.010. Cancer Cell. 2005. PMID: 16169468 Free article.
G'rab'bing the microenvironment for invasion.
Weaver V, Werb Z. Weaver V, et al. Dev Cell. 2007 Oct;13(4):462-3. doi: 10.1016/j.devcel.2007.09.013. Dev Cell. 2007. PMID: 17925222 Free article.
Matrix crosslinking forces tumor progression by enhancing integrin signaling.
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. Levental KR, et al. Among authors: weaver vm. Cell. 2009 Nov 25;139(5):891-906. doi: 10.1016/j.cell.2009.10.027. Cell. 2009. PMID: 19931152 Free PMC article.
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.
Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK, Welm AL, Feldman MD, Weber BL, Weaver VM. Gilbert PM, et al. Among authors: weaver vm. J Clin Invest. 2010 May;120(5):1535-50. doi: 10.1172/JCI39534. Epub 2010 Apr 12. J Clin Invest. 2010. PMID: 20389018 Free PMC article.
236 results