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Antisickling effect of chrysin is associated with modulation of oxygenated and deoxygenated haemoglobin via alteration of functional chemistry and metabolic pathways of human sickle erythrocytes.
Nwankwo HC, Idowu AA, Muhammad A, Waziri AD, Abubakar YS, Bashir M, Erukainure OL. Nwankwo HC, et al. Among authors: waziri ad. Hum Exp Toxicol. 2021 Dec;40(12_suppl):S108-S124. doi: 10.1177/09603271211025599. Epub 2021 Jun 21. Hum Exp Toxicol. 2021. PMID: 34151613
Sickling-suppressive effects of chrysin may be associated with sequestration of deoxy-haemoglobin, 2,3-bisphosphoglycerate mutase, alteration of redox homeostasis and functional chemistry of sickle erythrocytes.
Muhammad A, Waziri AD, Forcados GE, Sanusi B, Sani H, Malami I, Abubakar IB, Muhammad A, Muhammad RA, Mohammed HA. Muhammad A, et al. Among authors: waziri ad. Hum Exp Toxicol. 2020 Apr;39(4):537-546. doi: 10.1177/0960327119895815. Epub 2019 Dec 26. Hum Exp Toxicol. 2020. PMID: 31876182
Sickling-preventive effects of rutin is associated with modulation of deoxygenated haemoglobin, 2,3-bisphosphoglycerate mutase, redox status and alteration of functional chemistry in sickle erythrocytes.
Muhammad A, Waziri AD, Forcados GE, Sanusi B, Sani H, Malami I, Abubakar IB, Oluwatoyin HY, Adinoyi OA, Mohammed HA. Muhammad A, et al. Among authors: waziri ad. Heliyon. 2019 Jun 24;5(6):e01905. doi: 10.1016/j.heliyon.2019.e01905. eCollection 2019 Jun. Heliyon. 2019. PMID: 31297461 Free PMC article.