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Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies.
Nat Med. 2017 Dec;23(12):1416-1423. doi: 10.1038/nm.4444. Epub 2017 Nov 13.
Nat Med. 2017.
PMID: 29131157
Free article.
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.
Ghorashian S, Kramer AM, Onuoha S, Wright G, Bartram J, Richardson R, Albon SJ, Casanovas-Company J, Castro F, Popova B, Villanueva K, Yeung J, Vetharoy W, Guvenel A, Wawrzyniecka PA, Mekkaoui L, Cheung GW, Pinner D, Chu J, Lucchini G, Silva J, Ciocarlie O, Lazareva A, Inglott S, Gilmour KC, Ahsan G, Ferrari M, Manzoor S, Champion K, Brooks T, Lopes A, Hackshaw A, Farzaneh F, Chiesa R, Rao K, Bonney D, Samarasinghe S, Goulden N, Vora A, Veys P, Hough R, Wynn R, Pule MA, Amrolia PJ.
Ghorashian S, et al. Among authors: wawrzyniecka pa.
Nat Med. 2019 Sep;25(9):1408-1414. doi: 10.1038/s41591-019-0549-5. Epub 2019 Sep 2.
Nat Med. 2019.
PMID: 31477906
Clinical Trial.
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A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats.
Nannini F, Parekh F, Wawrzyniecka P, Mekkaoui L, Righi M, Dastjerdi FV, Yeung J, Roddie C, Bai Y, Ma B, Ferrari M, Onuoha S, Chester K, Pule M.
Nannini F, et al.
Sci Rep. 2020 Nov 5;10(1):19168. doi: 10.1038/s41598-020-76069-3.
Sci Rep. 2020.
PMID: 33154441
Free PMC article.
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Chimeric antigen receptor T cells for gamma-delta T cell malignancies.
Wawrzyniecka PA, Ibrahim L, Gritti G, Pule MA, Maciocia PM.
Wawrzyniecka PA, et al.
Leukemia. 2022 Feb;36(2):577-579. doi: 10.1038/s41375-021-01385-0. Epub 2021 Aug 13.
Leukemia. 2022.
PMID: 34389804
Free PMC article.
No abstract available.
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Tunable control of CAR T cell activity through tetracycline mediated disruption of protein-protein interaction.
Hotblack A, Kokalaki EK, Palton MJ, Cheung GW, Williams IP, Manzoor S, Grothier TI, Piapi A, Fiaccadori V, Wawrzyniecka P, Roddy HA, Agliardi G, Roddie C, Onuoha S, Thomas S, Cordoba S, Pule M.
Hotblack A, et al.
Sci Rep. 2021 Nov 9;11(1):21902. doi: 10.1038/s41598-021-01418-9.
Sci Rep. 2021.
PMID: 34754016
Free PMC article.
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Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia.
Maciocia PM, Wawrzyniecka PA, Maciocia NC, Burley A, Karpanasamy T, Devereaux S, Hoekx M, O'Connor D, Leon T, Rapoz-D'Silva T, Pocock R, Rahman S, Gritti G, Yánez DC, Ross S, Crompton T, Williams O, Lee L, Pule MA, Mansour MR.
Maciocia PM, et al. Among authors: wawrzyniecka pa.
Blood. 2022 Jul 7;140(1):25-37. doi: 10.1182/blood.2021013648.
Blood. 2022.
PMID: 35507686
Free article.
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Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy.
Lee L, Lim WC, Galas-Filipowicz D, Fung K, Taylor J, Patel D, Akbar Z, Alvarez Mediavilla E, Wawrzyniecka P, Shome D, Reijmers RM, Gregg T, Wood L, Day W, Cerec V, Ferrari M, Thomas S, Cordoba S, Onuoha S, Khokhar N, Peddareddigari V, Al-Hajj M, Cavet J, Zweegman S, Rodriguez-Justo M, Youg K, Pule M, Popat R.
Lee L, et al.
J Immunother Cancer. 2023 Jun;11(6):e006699. doi: 10.1136/jitc-2023-006699.
J Immunother Cancer. 2023.
PMID: 37399355
Free PMC article.
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