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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Among authors: wauters j. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Establishing a Unified COVID-19 "Immunome": Integrating Coronavirus Pathogenesis and Host Immunopathology.
Wauters E, Thevissen K, Wouters C, Bosisio FM, De Smet F, Gunst J, Humblet-Baron S, Lambrechts D, Liston A, Matthys P, Neyts J, Proost P, Weynand B, Wauters J, Tejpar S, Garg AD. Wauters E, et al. Among authors: wauters j. Front Immunol. 2020 Jul 3;11:1642. doi: 10.3389/fimmu.2020.01642. eCollection 2020. Front Immunol. 2020. PMID: 32719686 Free PMC article. No abstract available.
Intensive care unit acquired muscle weakness in COVID-19 patients.
Van Aerde N, Van den Berghe G, Wilmer A, Gosselink R, Hermans G; COVID-19 Consortium. Van Aerde N, et al. Intensive Care Med. 2020 Nov;46(11):2083-2085. doi: 10.1007/s00134-020-06244-7. Epub 2020 Sep 28. Intensive Care Med. 2020. PMID: 32986233 Free PMC article. No abstract available.
Development and External Validation of an Online Clinical Prediction Model for Augmented Renal Clearance in Adult Mixed Critically Ill Patients: The Augmented Renal Clearance Predictor.
Gijsen M, Huang CY, Flechet M, Van Daele R, Declercq P, Debaveye Y, Meersseman P, Meyfroidt G, Wauters J, Spriet I. Gijsen M, et al. Among authors: wauters j. Crit Care Med. 2020 Dec;48(12):e1260-e1268. doi: 10.1097/CCM.0000000000004667. Crit Care Med. 2020. PMID: 33048900
Increased IL-10-producing regulatory T cells are characteristic of severe cases of COVID-19.
Neumann J, Prezzemolo T, Vanderbeke L, Roca CP, Gerbaux M, Janssens S, Willemsen M, Burton O, Van Mol P, Van Herck Y; CONTAGIOUS co‐authors; Wauters J, Wauters E, Liston A, Humblet-Baron S. Neumann J, et al. Among authors: wauters e, wauters j. Clin Transl Immunology. 2020 Nov 13;9(11):e1204. doi: 10.1002/cti2.1204. eCollection 2020. Clin Transl Immunology. 2020. PMID: 33209300 Free PMC article.
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages.
Wauters E, Van Mol P, Garg AD, Jansen S, Van Herck Y, Vanderbeke L, Bassez A, Boeckx B, Malengier-Devlies B, Timmerman A, Van Brussel T, Van Buyten T, Schepers R, Heylen E, Dauwe D, Dooms C, Gunst J, Hermans G, Meersseman P, Testelmans D, Yserbyt J, Tejpar S, De Wever W, Matthys P; CONTAGIOUS collaborators; Neyts J, Wauters J, Qian J, Lambrechts D. Wauters E, et al. Among authors: wauters j. Cell Res. 2021 Mar;31(3):272-290. doi: 10.1038/s41422-020-00455-9. Epub 2021 Jan 21. Cell Res. 2021. PMID: 33473155 Free PMC article.
High dimensional profiling identifies specific immune types along the recovery trajectories of critically ill COVID19 patients.
Penttilä PA, Van Gassen S, Panovska D, Vanderbeke L, Van Herck Y, Quintelier K, Emmaneel A, Filtjens J, Malengier-Devlies B, Ahmadzadeh K, Van Mol P, Borràs DM, Antoranz A, Bosisio FM, Wauters E, Martinod K, Matthys P, Saeys Y, Garg AD, Wauters J, De Smet F; CONTAGIOUS consortium. Penttilä PA, et al. Among authors: wauters e, wauters j. Cell Mol Life Sci. 2021 Apr;78(8):3987-4002. doi: 10.1007/s00018-021-03808-8. Epub 2021 Mar 13. Cell Mol Life Sci. 2021. PMID: 33715015 Free PMC article.
Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019.
Metzemaekers M, Cambier S, Blanter M, Vandooren J, de Carvalho AC, Malengier-Devlies B, Vanderbeke L, Jacobs C, Coenen S, Martens E, Pörtner N, Vanbrabant L, Van Mol P, Van Herck Y, Van Aerde N, Hermans G, Gunst J, Borin A, Toledo N Pereira B, Dos Sp Gomes AB, Primon Muraro S, Fabiano de Souza G, S Farias A, Proenca-Modena JL, R Vinolo MA; CONTAGIOUS Consortium; Marques PE, Wouters C, Wauters E, Struyf S, Matthys P, Opdenakker G, Marques RE, Wauters J, Gouwy M, Proost P. Metzemaekers M, et al. Among authors: wauters e, wauters j. Clin Transl Immunology. 2021 Apr 29;10(4):e1271. doi: 10.1002/cti2.1271. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33968405 Free PMC article.
478 results