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Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.
Vibert J, Saulnier O, Collin C, Petit F, Borgman KJE, Vigneau J, Gautier M, Zaidi S, Pierron G, Watson S, Gruel N, Hénon C, Postel-Vinay S, Deloger M, Raynal V, Baulande S, Laud-Duval K, Hill V, Grossetête S, Dingli F, Loew D, Torrejon J, Ayrault O, Orth MF, Grünewald TGP, Surdez D, Coulon A, Waterfall JJ, Delattre O. Vibert J, et al. Among authors: watson s. Mol Cell. 2022 Jul 7;82(13):2458-2471.e9. doi: 10.1016/j.molcel.2022.04.019. Epub 2022 May 11. Mol Cell. 2022. PMID: 35550257 Free article.
SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas.
Le Loarer F, Watson S, Pierron G, de Montpreville VT, Ballet S, Firmin N, Auguste A, Pissaloux D, Boyault S, Paindavoine S, Dechelotte PJ, Besse B, Vignaud JM, Brevet M, Fadel E, Richer W, Treilleux I, Masliah-Planchon J, Devouassoux-Shisheboran M, Zalcman G, Allory Y, Bourdeaut F, Thivolet-Bejui F, Ranchere-Vince D, Girard N, Lantuejoul S, Galateau-Sallé F, Coindre JM, Leary A, Delattre O, Blay JY, Tirode F. Le Loarer F, et al. Among authors: watson s. Nat Genet. 2015 Oct;47(10):1200-5. doi: 10.1038/ng.3399. Epub 2015 Sep 7. Nat Genet. 2015. PMID: 26343384
Transcriptomic definition of molecular subgroups of small round cell sarcomas.
Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretière JM, Freneaux P, Le Loarer F, Bouvet M, Galmiche-Rolland L, Larousserie F, Longchampt E, Ranchere-Vince D, Pierron G, Delattre O, Tirode F. Watson S, et al. J Pathol. 2018 May;245(1):29-40. doi: 10.1002/path.5053. Epub 2018 Mar 30. J Pathol. 2018. PMID: 29431183
Identification of Tissue of Origin and Guided Therapeutic Applications in Cancers of Unknown Primary Using Deep Learning and RNA Sequencing (TransCUPtomics).
Vibert J, Pierron G, Benoist C, Gruel N, Guillemot D, Vincent-Salomon A, Le Tourneau C, Livartowski A, Mariani O, Baulande S, Bidard FC, Delattre O, Waterfall JJ, Watson S. Vibert J, et al. Among authors: watson s. J Mol Diagn. 2021 Oct;23(10):1380-1392. doi: 10.1016/j.jmoldx.2021.07.009. Epub 2021 Jul 26. J Mol Diagn. 2021. PMID: 34325056 Free article.
Novel EWSR1::UBP1 fusion expands the spectrum of spindle cell rhabdomyosarcomas.
El Zein S, Djeroudi L, Reynaud S, Guillemot D, Masliah-Planchon J, Frouin E, Nicolas N, Le Loarer F, Daniel C, Delattre O, Pierron G, Watson S. El Zein S, et al. Among authors: watson s. Genes Chromosomes Cancer. 2022 Apr;61(4):200-205. doi: 10.1002/gcc.23019. Epub 2021 Dec 14. Genes Chromosomes Cancer. 2022. PMID: 34877752
3,200 results