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Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension.
Valentine MS, Bender AM, Shay S, Paffenroth KC, Gladson S, Dickerson JW, Watson KJ, Kapolka NJ, Boutaud O, Rook JM, Blackwell TS, Roth BL, Harrison FE, Austin ED, West JD, Lindsley CW, Merryman WD. Valentine MS, et al. Among authors: watson kj. JACC Basic Transl Sci. 2023 Sep 13;8(10):1379-1388. doi: 10.1016/j.jacbts.2023.06.014. eCollection 2023 Oct. JACC Basic Transl Sci. 2023. PMID: 38094686 Free PMC article.
Common analysis of direct RNA sequencinG CUrrently leads to misidentification of m5C at GCU motifs.
Watson KJ, Bromley RE, Sparklin BC, Gasser MT, Bhattacharya T, Lebov JF, Tyson T, Dai N, Teigen LE, Graf KT, Foster JM, Michalski M, Bruno VM, Lindsey AR, Corrêa IR Jr, Hardy RW, Newton IL, Dunning Hotopp JC. Watson KJ, et al. Life Sci Alliance. 2023 Nov 29;7(2):e202302201. doi: 10.26508/lsa.202302201. Print 2024 Feb. Life Sci Alliance. 2023. PMID: 38030223 Free PMC article.
Common Analysis of Direct RNA SequencinG CUrrently Leads to Misidentification of 5-Methylcytosine Modifications at GCU Motifs.
Watson KJ, Bromley RE, Sparklin BC, Gasser MT, Bhattacharya T, Lebov JF, Tyson T, Teigen LE, Graf KT, Michalski M, Bruno VM, Lindsey ARI, Hardy RW, Newton ILG, Hotopp JCD. Watson KJ, et al. bioRxiv [Preprint]. 2023 May 3:2023.05.03.539298. doi: 10.1101/2023.05.03.539298. bioRxiv. 2023. PMID: 37205495 Free PMC article. Updated. Preprint.
Population Pharmacokinetic Modeling and Probability of Pharmacodynamic Target Attainment for Ceftazidime-Avibactam in Pediatric Patients Aged 3 Months and Older.
Franzese RC, McFadyen L, Watson KJ, Riccobene T, Carrothers TJ, Vourvahis M, Chan PLS, Raber S, Bradley JS, Lovern M. Franzese RC, et al. Among authors: watson kj. Clin Pharmacol Ther. 2022 Mar;111(3):635-645. doi: 10.1002/cpt.2460. Epub 2021 Nov 22. Clin Pharmacol Ther. 2022. PMID: 34687548 Free PMC article. Clinical Trial.
Discovery of the First Selective M4 Muscarinic Acetylcholine Receptor Antagonists with in Vivo Antiparkinsonian and Antidystonic Efficacy.
Moehle MS, Bender AM, Dickerson JW, Foster DJ, Qi A, Cho HP, Donsante Y, Peng W, Bryant Z, Stillwell KJ, Bridges TM, Chang S, Watson KJ, O'Neill JC, Engers JL, Peng L, Rodriguez AL, Niswender CM, Lindsley CW, Hess EJ, Conn PJ, Rook JM. Moehle MS, et al. Among authors: watson kj. ACS Pharmacol Transl Sci. 2021 Aug 2;4(4):1306-1321. doi: 10.1021/acsptsci.0c00162. eCollection 2021 Aug 13. ACS Pharmacol Transl Sci. 2021. PMID: 34423268 Free PMC article.
Discovery of VU6028418: A Highly Selective and Orally Bioavailable M4 Muscarinic Acetylcholine Receptor Antagonist.
Spock M, Carter TR, Bollinger KA, Han C, Baker LA, Rodriguez AL, Peng L, Dickerson JW, Qi A, Rook JM, O'Neill JC, Watson KJ, Chang S, Bridges TM, Engers JL, Engers DW, Niswender CM, Conn PJ, Lindsley CW, Bender AM. Spock M, et al. Among authors: watson kj. ACS Med Chem Lett. 2021 Aug 2;12(8):1342-1349. doi: 10.1021/acsmedchemlett.1c00363. eCollection 2021 Aug 12. ACS Med Chem Lett. 2021. PMID: 34413964 Free PMC article.
For sale: rare piece of polar paradise.
Watson KJ. Watson KJ. Med J Aust. 2020 Dec;213(11):525. doi: 10.5694/mja2.50867. Med J Aust. 2020. PMID: 33314110 No abstract available.
56 results