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Why is melanoma so metastatic?
Braeuer RR, Watson IR, Wu CJ, Mobley AK, Kamiya T, Shoshan E, Bar-Eli M. Braeuer RR, et al. Among authors: watson ir. Pigment Cell Melanoma Res. 2014 Jan;27(1):19-36. doi: 10.1111/pcmr.12172. Epub 2013 Oct 17. Pigment Cell Melanoma Res. 2014. PMID: 24106873 Review.
The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.
Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, Moreau Y, Marshall J, Ramakrishna M, Tarpey P, Shlien A, Whitmore I, Gamble S, Latimer C, Langdon E, Kaufman C, Dovey M, Taylor A, Menzies A, McLaren S, O'Meara S, Butler A, Teague J, Lister J, Chin L, Campbell P, Adams DJ, Zon LI, Patton EE, Stemple DL, Futreal PA. Yen J, et al. Among authors: watson ir. Genome Biol. 2013;14(10):R113. doi: 10.1186/gb-2013-14-10-r113. Genome Biol. 2013. PMID: 24148783 Free PMC article.
Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.
Stockman DL, Curry JL, Torres-Cabala CA, Watson IR, Siroy AE, Bassett RL, Zou L, Patel KP, Luthra R, Davies MA, Wargo JA, Routbort MA, Broaddus RR, Prieto VG, Lazar AJ, Tetzlaff MT. Stockman DL, et al. Among authors: watson ir. J Cutan Pathol. 2015 May;42(5):308-17. doi: 10.1111/cup.12481. Epub 2015 Mar 24. J Cutan Pathol. 2015. PMID: 25754356
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance.
Somasundaram R, Zhang G, Fukunaga-Kalabis M, Perego M, Krepler C, Xu X, Wagner C, Hristova D, Zhang J, Tian T, Wei Z, Liu Q, Garg K, Griss J, Hards R, Maurer M, Hafner C, Mayerhöfer M, Karanikas G, Jalili A, Bauer-Pohl V, Weihsengruber F, Rappersberger K, Koller J, Lang R, Hudgens C, Chen G, Tetzlaff M, Wu L, Frederick DT, Scolyer RA, Long GV, Damle M, Ellingsworth C, Grinman L, Choi H, Gavin BJ, Dunagin M, Raj A, Scholler N, Gross L, Beqiri M, Bennett K, Watson I, Schaider H, Davies MA, Wargo J, Czerniecki BJ, Schuchter L, Herlyn D, Flaherty K, Herlyn M, Wagner SN. Somasundaram R, et al. Nat Commun. 2017 Sep 19;8(1):607. doi: 10.1038/s41467-017-00452-4. Nat Commun. 2017. PMID: 28928360 Free PMC article. Clinical Trial.
A landscape of driver mutations in melanoma.
Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DS, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L. Hodis E, et al. Among authors: watson ir. Cell. 2012 Jul 20;150(2):251-63. doi: 10.1016/j.cell.2012.06.024. Cell. 2012. PMID: 22817889 Free PMC article.
The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.
Karachaliou GS, Alkallas R, Carroll SB, Caressi C, Zakria D, Patel NM, Trembath DG, Ezzell JA, Pegna GJ, Googe PB, Galeotti JP, Ayvali F, Collichio FA, Lee CB, Ollila DW, Gulley ML, Johnson DB, Kim KB, Watson IR, Moschos SJ. Karachaliou GS, et al. Among authors: watson ir. BMC Cancer. 2022 Jan 5;22(1):38. doi: 10.1186/s12885-021-08908-z. BMC Cancer. 2022. PMID: 34986841 Free PMC article.
Spatially mapping the immune landscape of melanoma using imaging mass cytometry.
Moldoveanu D, Ramsay L, Lajoie M, Anderson-Trocme L, Lingrand M, Berry D, Perus LJM, Wei Y, Moraes C, Alkallas R, Rajkumar S, Zuo D, Dankner M, Xu EH, Bertos NR, Najafabadi HS, Gravel S, Costantino S, Richer MJ, Lund AW, Del Rincon SV, Spatz A, Miller WH Jr, Jamal R, Lapointe R, Mes-Masson AM, Turcotte S, Petrecca K, Dumitra S, Meguerditchian AN, Richardson K, Tremblay F, Wang B, Chergui M, Guiot MC, Watters K, Stagg J, Quail DF, Mihalcioiu C, Meterissian S, Watson IR. Moldoveanu D, et al. Among authors: watson ir. Sci Immunol. 2022 Apr;7(70):eabi5072. doi: 10.1126/sciimmunol.abi5072. Epub 2022 Apr 1. Sci Immunol. 2022. PMID: 35363543
42 results