Watson IDG - Search Results

1

Leveraging Open Science Drug Development for PET: Preliminary Neuroimaging of ¹¹C-Labeled ALK2 Inhibitors.

Murrell E, Tong J, Smil D, Kiyota T, Aman AM, Isaac MB, Watson IDG, Vasdev N. Murrell E, et al. Among authors: watson idg. ACS Med Chem Lett. 2021 Apr 23;12(5):846-850. doi: 10.1021/acsmedchemlett.1c00127. eCollection 2021 May 13. ACS Med Chem Lett. 2021. PMID: 34055235 Free PMC article.

2

The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia.

Su Y, Carter JL, Li X, Fukuda Y, Gray A, Lynch J, Edwards H, Ma J, Schreiner P, Polin L, Kushner J, Dzinic SH, Buck SA, Pruett-Miller SM, Hege-Hurrish K, Robinson C, Qiao X, Liu S, Wu S, Wang G, Li J, Allen JE, Prabhu VV, Schimmer AD, Joshi D, Kalhor-Monfared S, Watson IDG, Marcellus R, Isaac MB, Al-Awar R, Taub JW, Lin H, Schuetz JD, Ge Y. Su Y, et al. Among authors: watson idg. Cancer Res. 2024 Apr 1;84(7):1084-1100. doi: 10.1158/0008-5472.CAN-23-2659. Cancer Res. 2024. PMID: 38266099

3

Rearrangement of 4-amino-3-halo-pyridines by nucleophilic aromatic substitution.

Getlik M, Wilson BJ, Morshed MM, Watson ID, Tang D, Subramanian P, Al-awar R. Getlik M, et al. J Org Chem. 2013 Jun 7;78(11):5705-10. doi: 10.1021/jo4003773. Epub 2013 May 23. J Org Chem. 2013. PMID: 23700973

4

Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors.

Mfuh AM, Boerth JA, Bommakanti G, Chan C, Chinn AJ, Code E, Fricke PJ, Giblin KA, Gohlke A, Hansel C, Hariparsad N, Hughes SJ, Jin M, Kantae V, Kavanagh SL, Lamb ML, Lane J, Moore R, Puri T, Quinn TR, Reddy I, Robb GR, Robbins KJ, Gancedo Rodrigo M, Schimpl M, Singh B, Singh M, Tang H, Thomson C, Walsh JJ, Ware J, Watson IDG, Ye MW, Wrigley GL, Zhang AX, Zhang Y, Grimster NP. Mfuh AM, et al. Among authors: watson idg. J Med Chem. 2024 Jan 25;67(2):1500-1512. doi: 10.1021/acs.jmedchem.3c02083. Epub 2024 Jan 16. J Med Chem. 2024. PMID: 38227216

5

Ring-opening reactions of nonactivated aziridines catalyzed by tris(pentafluorophenyl)borane.

Watson ID, Yudin AK. Watson ID, et al. J Org Chem. 2003 Jun 27;68(13):5160-7. doi: 10.1021/jo0343578. J Org Chem. 2003. PMID: 12816471

6

Achieving control over the branched/linear selectivity in palladium-catalyzed allylic amination.

Dubovyk I, Watson ID, Yudin AK. Dubovyk I, et al. J Org Chem. 2013 Feb 15;78(4):1559-75. doi: 10.1021/jo3025253. Epub 2013 Feb 6. J Org Chem. 2013. PMID: 23327430

7

Selective functionalization of small organic molecules using electrophilic nitrogen sources.

Watson ID, Yudin AK. Watson ID, et al. Curr Opin Drug Discov Devel. 2002 Nov;5(6):906-17. Curr Opin Drug Discov Devel. 2002. PMID: 12478721 Review.

8

Unusual selectivity of unprotected aziridines in palladium-catalyzed allylic amination enables facile preparation of branched aziridines.

Watson ID, Styler SA, Yudin AK. Watson ID, et al. J Am Chem Soc. 2004 Apr 28;126(16):5086-7. doi: 10.1021/ja049242f. J Am Chem Soc. 2004. PMID: 15099089

9

New insights into the mechanism of palladium-catalyzed allylic amination.

Watson ID, Yudin AK. Watson ID, et al. J Am Chem Soc. 2005 Dec 14;127(49):17516-29. doi: 10.1021/ja055288c. J Am Chem Soc. 2005. PMID: 16332104

10

Advances in nitrogen transfer reactions involving aziridines.

Watson ID, Yu L, Yudin AK. Watson ID, et al. Acc Chem Res. 2006 Mar;39(3):194-206. doi: 10.1021/ar050038m. Acc Chem Res. 2006. PMID: 16548508

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