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The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells.
Murakami Y, Sonoda K, Abe H, Watari K, Kusakabe D, Azuma K, Kawahara A, Akiba J, Oneyama C, Pachter JA, Sakai K, Nishio K, Kuwano M, Ono M. Murakami Y, et al. Among authors: watari k. Oncotarget. 2017 Aug 7;8(41):70736-70751. doi: 10.18632/oncotarget.19982. eCollection 2017 Sep 19. Oncotarget. 2017. PMID: 29050315 Free PMC article.
129 results