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Combined inhibition of XIAP and BCL2 drives maximal therapeutic efficacy in genetically diverse aggressive acute myeloid leukemia.
Hashimoto M, Saito Y, Nakagawa R, Ogahara I, Takagi S, Takata S, Amitani H, Endo M, Yuki H, Ramilowski JA, Severin J, Manabe RI, Watanabe T, Ozaki K, Kaneko A, Kajita H, Fujiki S, Sato K, Honma T, Uchida N, Fukami T, Okazaki Y, Ohara O, Shultz LD, Yamada M, Taniguchi S, Vyas P, de Hoon M, Momozawa Y, Ishikawa F. Hashimoto M, et al. Among authors: watanabe t. Nat Cancer. 2021 Mar;2(3):340-356. doi: 10.1038/s43018-021-00177-w. Epub 2021 Mar 18. Nat Cancer. 2021. PMID: 35121960
Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia.
Aoki Y, Watanabe T, Saito Y, Kuroki Y, Hijikata A, Takagi M, Tomizawa D, Eguchi M, Eguchi-Ishimae M, Kaneko A, Ono R, Sato K, Suzuki N, Fujiki S, Koh K, Ishii E, Shultz LD, Ohara O, Mizutani S, Ishikawa F. Aoki Y, et al. Among authors: watanabe t. Blood. 2015 Feb 5;125(6):967-80. doi: 10.1182/blood-2014-03-563304. Epub 2014 Dec 23. Blood. 2015. PMID: 25538041 Free PMC article.
Protective neutralizing influenza antibody response in the absence of T follicular helper cells.
Miyauchi K, Sugimoto-Ishige A, Harada Y, Adachi Y, Usami Y, Kaji T, Inoue K, Hasegawa H, Watanabe T, Hijikata A, Fukuyama S, Maemura T, Okada-Hatakeyama M, Ohara O, Kawaoka Y, Takahashi Y, Takemori T, Kubo M. Miyauchi K, et al. Among authors: watanabe t. Nat Immunol. 2016 Dec;17(12):1447-1458. doi: 10.1038/ni.3563. Epub 2016 Oct 31. Nat Immunol. 2016. PMID: 27798619
Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways.
Saito Y, Mochizuki Y, Ogahara I, Watanabe T, Hogdal L, Takagi S, Sato K, Kaneko A, Kajita H, Uchida N, Fukami T, Shultz LD, Taniguchi S, Ohara O, Letai AG, Ishikawa F. Saito Y, et al. Among authors: watanabe t. Sci Transl Med. 2017 Oct 25;9(413):eaao1214. doi: 10.1126/scitranslmed.aao1214. Sci Transl Med. 2017. PMID: 29070697 Free PMC article.
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