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SGLT-1-specific inhibition ameliorates renal failure and alters the gut microbial community in mice with adenine-induced renal failure.
Ho HJ, Kikuchi K, Oikawa D, Watanabe S, Kanemitsu Y, Saigusa D, Kujirai R, Ikeda-Ohtsubo W, Ichijo M, Akiyama Y, Aoki Y, Mishima E, Ogata Y, Oikawa Y, Matsuhashi T, Toyohara T, Suzuki C, Suzuki T, Mano N, Kagawa Y, Owada Y, Katayama T, Nakayama T, Tomioka Y, Abe T. Ho HJ, et al. Among authors: watanabe s. Physiol Rep. 2021 Dec;9(24):e15092. doi: 10.14814/phy2.15092. Physiol Rep. 2021. PMID: 34921520 Free PMC article.
Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases.
Suzuki T, Yamaguchi H, Kikusato M, Matsuhashi T, Matsuo A, Sato T, Oba Y, Watanabe S, Minaki D, Saigusa D, Shimbo H, Mori N, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Yuri A, Kikuchi K, Toyohara T, Suzuki C, Kohzuki M, Anzai J, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Ito S, Osaka H, Hayashi K, Abe T. Suzuki T, et al. Among authors: watanabe s. Tohoku J Exp Med. 2015 Jul;236(3):225-32. doi: 10.1620/tjem.236.225. Tohoku J Exp Med. 2015. PMID: 26118651 Free article.
Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage.
Suzuki T, Yamaguchi H, Kikusato M, Hashizume O, Nagatoishi S, Matsuo A, Sato T, Kudo T, Matsuhashi T, Murayama K, Ohba Y, Watanabe S, Kanno S, Minaki D, Saigusa D, Shinbo H, Mori N, Yuri A, Yokoro M, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Kikuchi K, Toyohara T, Suzuki C, Ichimura T, Anzai J, Kohzuki M, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Tsumoto K, Nakada K, Bonventre JV, Ito S, Osaka H, Hayashi K, Abe T. Suzuki T, et al. Among authors: watanabe s. J Am Soc Nephrol. 2016 Jul;27(7):1925-32. doi: 10.1681/ASN.2015060623. Epub 2015 Nov 25. J Am Soc Nephrol. 2016. PMID: 26609120 Free PMC article.
A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathways.
Shima H, Sasaki K, Suzuki T, Mukawa C, Obara T, Oba Y, Matsuo A, Kobayashi T, Mishima E, Watanabe S, Akiyama Y, Kikuchi K, Matsuhashi T, Oikawa Y, Nanto F, Akiyama Y, Ho HJ, Suzuki C, Saigusa D, Masamune A, Tomioka Y, Masaki T, Ito S, Hayashi KI, Abe T. Shima H, et al. Among authors: watanabe s. Sci Rep. 2017 May 15;7(1):1884. doi: 10.1038/s41598-017-01702-7. Sci Rep. 2017. PMID: 28507324 Free PMC article.
Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5.
Oikawa Y, Izumi R, Koide M, Hagiwara Y, Kanzaki M, Suzuki N, Kikuchi K, Matsuhashi T, Akiyama Y, Ichijo M, Watanabe S, Toyohara T, Suzuki T, Mishima E, Akiyama Y, Ogata Y, Suzuki C, Hayashi H, Kodama EN, Hayashi KI, Itoi E, Aoki M, Kure S, Abe T. Oikawa Y, et al. Among authors: watanabe s. PLoS One. 2020 Dec 2;15(12):e0231064. doi: 10.1371/journal.pone.0231064. eCollection 2020. PLoS One. 2020. PMID: 33264289 Free PMC article.
Development of osmotic vacuolization of proximal tubular epithelial cells following treatment with sodium-glucose transport protein 2 inhibitors in type II diabetes mellitus patients-3 case reports.
Watanabe S, Sawa N, Mizuno H, Yamanouchi M, Suwabe T, Hoshino J, Kinowaki K, Ohashi K, Fujii T, Yamaguchi Y, Ubara Y. Watanabe S, et al. CEN Case Rep. 2021 Nov;10(4):563-569. doi: 10.1007/s13730-021-00609-7. Epub 2021 May 22. CEN Case Rep. 2021. PMID: 34021486 Free PMC article.
Marked reduction of proteinuria after removal of a growth hormone-producing pituitary adenoma in a patient with focal segmental glomerulosclerosis: a case report and literature review.
Ishigaki S, Oe Y, Omata K, Ono Y, Tezuka Y, Morimoto R, Watanabe S, Nishioka H, Satoh F, Yoshida M, Makino R, Okamoto K, Nagasawa T, Inoshita N, Yamada S, Sato H, Ito S, Miyazaki M. Ishigaki S, et al. Among authors: watanabe s. CEN Case Rep. 2023 May;12(2):164-170. doi: 10.1007/s13730-022-00739-6. Epub 2022 Oct 6. CEN Case Rep. 2023. PMID: 36201148 Free PMC article. Review.
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