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PRC2 is dispensable for HOTAIR-mediated transcriptional repression.
Portoso M, Ragazzini R, Brenčič Ž, Moiani A, Michaud A, Vassilev I, Wassef M, Servant N, Sargueil B, Margueron R. Portoso M, et al. Among authors: wassef m. EMBO J. 2017 Apr 13;36(8):981-994. doi: 10.15252/embj.201695335. Epub 2017 Feb 6. EMBO J. 2017. PMID: 28167697 Free PMC article.
The Multiple Facets of PRC2 Alterations in Cancers.
Wassef M, Margueron R. Wassef M, et al. J Mol Biol. 2017 Jun 30;429(13):1978-1993. doi: 10.1016/j.jmb.2016.10.012. Epub 2016 Oct 12. J Mol Biol. 2017. PMID: 27742591 Review.
Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.
Sanulli S, Justin N, Teissandier A, Ancelin K, Portoso M, Caron M, Michaud A, Lombard B, da Rocha ST, Offer J, Loew D, Servant N, Wassef M, Burlina F, Gamblin SJ, Heard E, Margueron R. Sanulli S, et al. Among authors: wassef m. Mol Cell. 2015 Mar 5;57(5):769-783. doi: 10.1016/j.molcel.2014.12.020. Epub 2015 Jan 22. Mol Cell. 2015. PMID: 25620564 Free PMC article.
Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis.
Wassef M, Rodilla V, Teissandier A, Zeitouni B, Gruel N, Sadacca B, Irondelle M, Charruel M, Ducos B, Michaud A, Caron M, Marangoni E, Chavrier P, Le Tourneau C, Kamal M, Pasmant E, Vidaud M, Servant N, Reyal F, Meseure D, Vincent-Salomon A, Fre S, Margueron R. Wassef M, et al. Genes Dev. 2015 Dec 15;29(24):2547-62. doi: 10.1101/gad.269522.115. Epub 2015 Dec 4. Genes Dev. 2015. PMID: 26637281 Free PMC article.
BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation.
Campagne A, Lee MK, Zielinski D, Michaud A, Le Corre S, Dingli F, Chen H, Shahidian LZ, Vassilev I, Servant N, Loew D, Pasmant E, Postel-Vinay S, Wassef M, Margueron R. Campagne A, et al. Among authors: wassef m. Nat Commun. 2019 Jan 21;10(1):348. doi: 10.1038/s41467-018-08255-x. Nat Commun. 2019. PMID: 30664650 Free PMC article.
EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.
Wassef M, Luscan A, Aflaki S, Zielinski D, Jansen PWTC, Baymaz HI, Battistella A, Kersouani C, Servant N, Wallace MR, Romero P, Kosmider O, Just PA, Hivelin M, Jacques S, Vincent-Salomon A, Vermeulen M, Vidaud M, Pasmant E, Margueron R. Wassef M, et al. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6075-6080. doi: 10.1073/pnas.1814634116. Epub 2019 Mar 13. Proc Natl Acad Sci U S A. 2019. PMID: 30867289 Free PMC article.
"MPNST Epigenetics"-Letter.
Wassef M, Pasmant E, Margueron R. Wassef M, et al. Mol Cancer Res. 2019 Oct;17(10):2139. doi: 10.1158/1541-7786.MCR-19-0680. Mol Cancer Res. 2019. PMID: 31575727 No abstract available.
410 results