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Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue.
Weekman EM, Winder Z, Rogers CB, Abner EL, Sudduth TL, Patel E, Dugan AJ, Fister SX, Wasek B, Nelson PT, Jicha GA, Bottiglieri T, Fardo DW, Wilcock DM. Weekman EM, et al. Among authors: wasek b. Alzheimers Dement (N Y). 2022 Dec 8;8(1):e12368. doi: 10.1002/trc2.12368. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 36514441 Free PMC article.
PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments.
Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O. Nicholls RE, et al. Among authors: wasek b. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3347-52. doi: 10.1073/pnas.1521018113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951658 Free PMC article.
Dysregulation of methionine metabolism in multiple sclerosis.
Singhal NK, Freeman E, Arning E, Wasek B, Clements R, Sheppard C, Blake P, Bottiglieri T, McDonough J. Singhal NK, et al. Among authors: wasek b. Neurochem Int. 2018 Jan;112:1-4. doi: 10.1016/j.neuint.2017.10.011. Epub 2017 Oct 26. Neurochem Int. 2018. PMID: 29080803
Neuropathology of vitamin B12 deficiency in the Cd320-/- mouse.
Arora K, Sequeira JM, Alarcon JM, Wasek B, Arning E, Bottiglieri T, Quadros EV. Arora K, et al. Among authors: wasek b. FASEB J. 2019 Feb;33(2):2563-2573. doi: 10.1096/fj.201800754RR. Epub 2018 Oct 10. FASEB J. 2019. PMID: 30303736 Free PMC article.
Although the metabolic basis for the demyelination and the structural and functional alterations of the nervous system in Cbl deficiency remain unresolved, the Cd320(-/-) mouse provides a unique model to investigate the pathologic consequences of vitamin B(12) deficiency. …
Although the metabolic basis for the demyelination and the structural and functional alterations of the nervous system in Cbl deficiency rem …
32 results