Betaine attenuates pathology by stimulating lipid oxidation in liver and regulating phospholipid metabolism in brain of methionine-choline-deficient rats.
Abu Ahmad N, Raizman M, Weizmann N, Wasek B, Arning E, Bottiglieri T, Tirosh O, Troen AM.
Abu Ahmad N, et al. Among authors: wasek b.
FASEB J. 2019 Aug;33(8):9334-9349. doi: 10.1096/fj.201802683R. Epub 2019 May 23.
FASEB J. 2019.
PMID: 31120771
We fed male Sprague-Dawley rats a control diet, MCD diet, or betaine-supplemented MCD (MCD+B) diet for 8 wk and collected blood and tissue. As expected, betaine prevented MCD diet-induced NASH. ...The protective effect of betaine is likely due to the stimulation of beta-ox …
We fed male Sprague-Dawley rats a control diet, MCD diet, or betaine-supplemented MCD (MCD+B) diet for 8 wk and collected blood and t …