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Betaine attenuates pathology by stimulating lipid oxidation in liver and regulating phospholipid metabolism in brain of methionine-choline-deficient rats.
Abu Ahmad N, Raizman M, Weizmann N, Wasek B, Arning E, Bottiglieri T, Tirosh O, Troen AM. Abu Ahmad N, et al. Among authors: wasek b. FASEB J. 2019 Aug;33(8):9334-9349. doi: 10.1096/fj.201802683R. Epub 2019 May 23. FASEB J. 2019. PMID: 31120771
We fed male Sprague-Dawley rats a control diet, MCD diet, or betaine-supplemented MCD (MCD+B) diet for 8 wk and collected blood and tissue. As expected, betaine prevented MCD diet-induced NASH. ...The protective effect of betaine is likely due to the stimulation of beta-ox …
We fed male Sprague-Dawley rats a control diet, MCD diet, or betaine-supplemented MCD (MCD+B) diet for 8 wk and collected blood and t …
PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments.
Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O. Nicholls RE, et al. Among authors: wasek b. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3347-52. doi: 10.1073/pnas.1521018113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951658 Free PMC article.
Dysregulation of methionine metabolism in multiple sclerosis.
Singhal NK, Freeman E, Arning E, Wasek B, Clements R, Sheppard C, Blake P, Bottiglieri T, McDonough J. Singhal NK, et al. Among authors: wasek b. Neurochem Int. 2018 Jan;112:1-4. doi: 10.1016/j.neuint.2017.10.011. Epub 2017 Oct 26. Neurochem Int. 2018. PMID: 29080803
32 results