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Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice.
Malla SR, Krueger B, Wartmann T, Sendler M, Mahajan UM, Weiss FU, Thiel FG, De Boni C, Gorelick FS, Halangk W, Aghdassi AA, Reinheckel T, Gukovskaya AS, Lerch MM, Mayerle J. Malla SR, et al. Among authors: wartmann t. Cell Mol Life Sci. 2020 May;77(9):1811-1825. doi: 10.1007/s00018-019-03254-7. Epub 2019 Jul 30. Cell Mol Life Sci. 2020. PMID: 31363815 Free PMC article.
Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.
Wartmann T, Mayerle J, Kähne T, Sahin-Tóth M, Ruthenbürger M, Matthias R, Kruse A, Reinheckel T, Peters C, Weiss FU, Sendler M, Lippert H, Schulz HU, Aghdassi A, Dummer A, Teller S, Halangk W, Lerch MM. Wartmann T, et al. Gastroenterology. 2010 Feb;138(2):726-37. doi: 10.1053/j.gastro.2009.10.048. Epub 2009 Nov 10. Gastroenterology. 2010. PMID: 19900452 Free PMC article.
Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis.
Sendler M, Beyer G, Mahajan UM, Kauschke V, Maertin S, Schurmann C, Homuth G, Völker U, Völzke H, Halangk W, Wartmann T, Weiss FU, Hegyi P, Lerch MM, Mayerle J. Sendler M, et al. Among authors: wartmann t. Gastroenterology. 2015 Sep;149(3):765-76.e10. doi: 10.1053/j.gastro.2015.05.012. Epub 2015 May 19. Gastroenterology. 2015. PMID: 26001927 Free PMC article.
Legumain is activated in macrophages during pancreatitis.
Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, Storz P, Halangk W, Bogyo M, Bunnett NW. Edgington-Mitchell LE, et al. Among authors: wartmann t. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G548-60. doi: 10.1152/ajpgi.00047.2016. Epub 2016 Aug 11. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27514475 Free PMC article.
Deletion of IκBα activates RelA to reduce acute pancreatitis in mice through up-regulation of Spi2A.
Neuhöfer P, Liang S, Einwächter H, Schwerdtfeger C, Wartmann T, Treiber M, Zhang H, Schulz HU, Dlubatz K, Lesina M, Diakopoulos KN, Wörmann S, Halangk W, Witt H, Schmid RM, Algül H. Neuhöfer P, et al. Among authors: wartmann t. Gastroenterology. 2013 Jan;144(1):192-201. doi: 10.1053/j.gastro.2012.09.058. Epub 2012 Oct 3. Gastroenterology. 2013. PMID: 23041330
51 results