Warren DT - Search Results

1

N-terminal nesprin-2 variants regulate β-catenin signalling.

Zhang Q, Minaisah RM, Ferraro E, Li C, Porter LJ, Zhou C, Gao F, Zhang J, Rajgor D, Autore F, Shanahan CM, Warren DT. Zhang Q, et al. Among authors: warren dt. Exp Cell Res. 2016 Jul 15;345(2):168-79. doi: 10.1016/j.yexcr.2016.06.008. Epub 2016 Jun 16. Exp Cell Res. 2016. PMID: 27321956 Free PMC article.

2

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle.

Zhang Q, Ragnauth CD, Skepper JN, Worth NF, Warren DT, Roberts RG, Weissberg PL, Ellis JA, Shanahan CM. Zhang Q, et al. Among authors: warren dt. J Cell Sci. 2005 Feb 15;118(Pt 4):673-87. doi: 10.1242/jcs.01642. Epub 2005 Jan 25. J Cell Sci. 2005. PMID: 15671068

3

Nesprins: intracellular scaffolds that maintain cell architecture and coordinate cell function?

Warren DT, Zhang Q, Weissberg PL, Shanahan CM. Warren DT, et al. Expert Rev Mol Med. 2005 Jun 13;7(11):1-15. doi: 10.1017/S1462399405009294. Expert Rev Mol Med. 2005. PMID: 15953398 Review.

4

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

Zhang Q, Bethmann C, Worth NF, Davies JD, Wasner C, Feuer A, Ragnauth CD, Yi Q, Mellad JA, Warren DT, Wheeler MA, Ellis JA, Skepper JN, Vorgerd M, Schlotter-Weigel B, Weissberg PL, Roberts RG, Wehnert M, Shanahan CM. Zhang Q, et al. Among authors: warren dt. Hum Mol Genet. 2007 Dec 1;16(23):2816-33. doi: 10.1093/hmg/ddm238. Epub 2007 Aug 29. Hum Mol Genet. 2007. PMID: 17761684

5

Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation.

Warren DT, Tajsic T, Mellad JA, Searles R, Zhang Q, Shanahan CM. Warren DT, et al. J Biol Chem. 2010 Jan 8;285(2):1311-20. doi: 10.1074/jbc.M109.032557. Epub 2009 Oct 27. J Biol Chem. 2010. PMID: 19861416 Free PMC article.

6

Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging.

Ragnauth CD, Warren DT, Liu Y, McNair R, Tajsic T, Figg N, Shroff R, Skepper J, Shanahan CM. Ragnauth CD, et al. Among authors: warren dt. Circulation. 2010 May 25;121(20):2200-10. doi: 10.1161/CIRCULATIONAHA.109.902056. Epub 2010 May 10. Circulation. 2010. PMID: 20458013

7

Nesprins LINC the nucleus and cytoskeleton.

Mellad JA, Warren DT, Shanahan CM. Mellad JA, et al. Among authors: warren dt. Curr Opin Cell Biol. 2011 Feb;23(1):47-54. doi: 10.1016/j.ceb.2010.11.006. Epub 2010 Dec 20. Curr Opin Cell Biol. 2011. PMID: 21177090 Review.

8

Defective DNA-damage repair induced by nuclear lamina dysfunction is a key mediator of smooth muscle cell aging.

Warren DT, Shanahan CM. Warren DT, et al. Biochem Soc Trans. 2011 Dec;39(6):1780-5. doi: 10.1042/BST20110703. Biochem Soc Trans. 2011. PMID: 22103525 Review.

9

Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing.

Warren DT, Tajsic T, Porter LJ, Minaisah RM, Cobb A, Jacob A, Rajgor D, Zhang QP, Shanahan CM. Warren DT, et al. Cell Death Differ. 2015 Sep;22(9):1540-50. doi: 10.1038/cdd.2015.12. Epub 2015 Mar 6. Cell Death Differ. 2015. PMID: 25744025 Free PMC article.

10

The Use of Polyacrylamide Hydrogels to Study the Effects of Matrix Stiffness on Nuclear Envelope Properties.

Minaisah RM, Cox S, Warren DT. Minaisah RM, et al. Among authors: warren dt. Methods Mol Biol. 2016;1411:233-9. doi: 10.1007/978-1-4939-3530-7_15. Methods Mol Biol. 2016. PMID: 27147046

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