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Direct targeted therapy for MLL-fusion-driven high-risk acute leukaemias.
Cantilena S, Gasparoli L, Pal D, Heidenreich O, Klusmann JH, Martens JHA, Faille A, Warren AJ, Karsa M, Pandher R, Somers K, Williams O, de Boer J. Cantilena S, et al. Among authors: warren aj. Clin Transl Med. 2022 Jun;12(6):e933. doi: 10.1002/ctm2.933. Clin Transl Med. 2022. PMID: 35730653 Free PMC article.
Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Zyryanova AF, Weis F, Faille A, Alard AA, Crespillo-Casado A, Sekine Y, Harding HP, Allen F, Parts L, Fromont C, Fischer PM, Warren AJ, Ron D. Zyryanova AF, et al. Among authors: warren aj. Science. 2018 Mar 30;359(6383):1533-1536. doi: 10.1126/science.aar5129. Science. 2018. PMID: 29599245 Free PMC article.
Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Kargas V, Castro-Hartmann P, Escudero-Urquijo N, Dent K, Hilcenko C, Sailer C, Zisser G, Marques-Carvalho MJ, Pellegrino S, Wawiórka L, Freund SM, Wagstaff JL, Andreeva A, Faille A, Chen E, Stengel F, Bergler H, Warren AJ. Kargas V, et al. Among authors: warren aj. Elife. 2019 May 22;8:e44904. doi: 10.7554/eLife.44904. Elife. 2019. PMID: 31115337 Free PMC article.
eIF6 rebinding dynamically couples ribosome maturation and translation.
Jaako P, Faille A, Tan S, Wong CC, Escudero-Urquijo N, Castro-Hartmann P, Wright P, Hilcenko C, Adams DJ, Warren AJ. Jaako P, et al. Among authors: warren aj. Nat Commun. 2022 Mar 23;13(1):1562. doi: 10.1038/s41467-022-29214-7. Nat Commun. 2022. PMID: 35322020 Free PMC article.
Teaching old drugs new tricks.
Faille A, Warren AJ. Faille A, et al. Among authors: warren aj. Elife. 2022 Dec 8;11:e84702. doi: 10.7554/eLife.84702. Elife. 2022. PMID: 36480270 Free PMC article.
EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome.
Tan S, Kermasson L, Hoslin A, Jaako P, Faille A, Acevedo-Arozena A, Lengline E, Ranta D, Poirée M, Fenneteau O, Ducou le Pointe H, Fumagalli S, Beaupain B, Nitschké P, Bôle-Feysot C, de Villartay JP, Bellanné-Chantelot C, Donadieu J, Kannengiesser C, Warren AJ, Revy P. Tan S, et al. Among authors: warren aj. Blood. 2019 Jul 18;134(3):277-290. doi: 10.1182/blood.2018893404. Epub 2019 May 31. Blood. 2019. PMID: 31151987 Free PMC article.
Somatic genetic rescue of a germline ribosome assembly defect.
Tan S, Kermasson L, Hilcenko C, Kargas V, Traynor D, Boukerrou AZ, Escudero-Urquijo N, Faille A, Bertrand A, Rossmann M, Goyenechea B, Jin L, Moreil J, Alibeu O, Beaupain B, Bôle-Feysot C, Fumagalli S, Kaltenbach S, Martignoles JA, Masson C, Nitschké P, Parisot M, Pouliet A, Radford-Weiss I, Tores F, de Villartay JP, Zarhrate M, Koh AL, Phua KB, Reversade B, Bond PJ, Bellanné-Chantelot C, Callebaut I, Delhommeau F, Donadieu J, Warren AJ, Revy P. Tan S, et al. Among authors: warren aj. Nat Commun. 2021 Aug 19;12(1):5044. doi: 10.1038/s41467-021-24999-5. Nat Commun. 2021. PMID: 34413298 Free PMC article.
Road to RIO-kinase 2 for AML therapy.
Warren AJ. Warren AJ. Blood. 2022 Jan 13;139(2):156-157. doi: 10.1182/blood.2021013618. Blood. 2022. PMID: 35024808 Free article. No abstract available.
Publisher Correction: Somatic genetic rescue of a germline ribosome assembly defect.
Tan S, Kermasson L, Hilcenko C, Kargas V, Traynor D, Boukerrou AZ, Escudero-Urquijo N, Faille A, Bertrand A, Rossmann M, Goyenechea B, Jin L, Moreil J, Alibeu O, Beaupain B, Bôle-Feysot C, Fumagalli S, Kaltenbach S, Martignoles JA, Masson C, Nitschké P, Parisot M, Pouliet A, Radford-Weiss I, Tores F, de Villartay JP, Zarhrate M, Koh AL, Phua KB, Reversade B, Bond PJ, Bellanné-Chantelot C, Callebaut I, Delhommeau F, Donadieu J, Warren AJ, Revy P. Tan S, et al. Among authors: warren aj. Nat Commun. 2022 Jun 22;13(1):3574. doi: 10.1038/s41467-022-31316-1. Nat Commun. 2022. PMID: 35732670 Free PMC article. No abstract available.
124 results