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Huntington disease: natural history, biomarkers and prospects for therapeutics.
Ross CA, Aylward EH, Wild EJ, Langbehn DR, Long JD, Warner JH, Scahill RI, Leavitt BR, Stout JC, Paulsen JS, Reilmann R, Unschuld PG, Wexler A, Margolis RL, Tabrizi SJ. Ross CA, et al. Among authors: warner jh. Nat Rev Neurol. 2014 Apr;10(4):204-16. doi: 10.1038/nrneurol.2014.24. Epub 2014 Mar 11. Nat Rev Neurol. 2014. PMID: 24614516 Free article. Review.
Assessment of motor symptoms and functional impact in prodromal and early huntington disease.
Vaccarino AL, Sills T, Anderson KE, Biglan K, Borowsky B, Giuliano J, Guttman M, Ho AK, Kennard C, Kupchak P, Landwehrmeyer GB, Michell A, Paulsen JS, Reilmann R, van Kammen DP, Warner JH, Evans K. Vaccarino AL, et al. Among authors: warner jh. PLoS Curr. 2011 Jun 14;2:RRN1244. doi: 10.1371/currents.RRN1244. PLoS Curr. 2011. PMID: 21804956 Free PMC article.
Indexing disease progression at study entry with individuals at-risk for Huntington disease.
Zhang Y, Long JD, Mills JA, Warner JH, Lu W, Paulsen JS; PREDICT-HD Investigators and Coordinators of the Huntington Study Group. Zhang Y, et al. Among authors: warner jh. Am J Med Genet B Neuropsychiatr Genet. 2011 Dec;156B(7):751-63. doi: 10.1002/ajmg.b.31232. Epub 2011 Aug 19. Am J Med Genet B Neuropsychiatr Genet. 2011. PMID: 21858921 Free PMC article.
Assessment of Day-to-Day Functioning in Prodromal and Early Huntington Disease.
Vaccarino AL, Sills T, Anderson KE, Endicott J, Giuliano J, Guttman M, Ho AK, Kupchak P, Paulsen JS, Warner JH, Williams J, Evans K. Vaccarino AL, et al. Among authors: warner jh. PLoS Curr. 2011 Sep 12;3:RRN1262. doi: 10.1371/currents.RRN1262. PLoS Curr. 2011. PMID: 21927718 Free PMC article.
CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion.
Lee JM, Ramos EM, Lee JH, Gillis T, Mysore JS, Hayden MR, Warby SC, Morrison P, Nance M, Ross CA, Margolis RL, Squitieri F, Orobello S, Di Donato S, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, Paulsen JS; PREDICT-HD study of the Huntington Study Group (HSG); Landwehrmeyer GB; REGISTRY study of the European Huntington's Disease Network; Myers RH; HD-MAPS Study Group; MacDonald ME, Gusella JF; COHORT study of the HSG. Lee JM, et al. Neurology. 2012 Mar 6;78(10):690-5. doi: 10.1212/WNL.0b013e318249f683. Epub 2012 Feb 8. Neurology. 2012. PMID: 22323755 Free PMC article.
8OHdG is not a biomarker for Huntington disease state or progression.
Borowsky B, Warner J, Leavitt BR, Tabrizi SJ, Roos RA, Durr A, Becker C, Sampaio C, Tobin AJ, Schulman H. Borowsky B, et al. Neurology. 2013 May 21;80(21):1934-41. doi: 10.1212/WNL.0b013e318293e1a1. Epub 2013 Apr 24. Neurology. 2013. PMID: 23616162 Free PMC article. Clinical Trial.
279 results