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Page 1
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Brown AJH, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L, Dias JM, Errey JC, Hurrell E, Liptrot J, Mattedi G, Molloy C, Nathan PJ, Okrasa K, Osborne G, Patel JC, Pickworth M, Robertson N, Shahabi S, Bundgaard C, Phillips K, Broad LM, Goonawardena AV, Morairty SR, Browning M, Perini F, Dawson GR, Deakin JFW, Smith RT, Sexton PM, Warneck J, Vinson M, Tasker T, Tehan BG, Teobald B, Christopoulos A, Langmead CJ, Jazayeri A, Cooke RM, Rucktooa P, Congreve MS, Weir M, Tobin AB. Brown AJH, et al. Among authors: warneck j. Cell. 2021 Nov 24;184(24):5886-5901.e22. doi: 10.1016/j.cell.2021.11.001. Cell. 2021. PMID: 34822784 Free article. Clinical Trial.
7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma.
Buckley GM, Cooper N, Davenport RJ, Dyke HJ, Galleway FP, Gowers L, Haughan AF, Kendall HJ, Lowe C, Montana JG, Oxford J, Peake JC, Picken CL, Richard MD, Sabin V, Sharpe A, Warneck JB. Buckley GM, et al. Among authors: warneck jb. Bioorg Med Chem Lett. 2002 Feb 11;12(3):509-12. doi: 10.1016/s0960-894x(01)00786-7. Bioorg Med Chem Lett. 2002. PMID: 11814830
8-Methoxyquinoline-5-carboxamides as PDE4 inhibitors: a potential treatment for asthma.
Buckley GM, Cooper N, Dyke HJ, Galleway FP, Gowers L, Haughan AF, Kendall HJ, Lowe C, Maxey R, Montana JG, Naylor R, Oxford J, Peake JC, Picken CL, Runcie KA, Sabin V, Sharpe A, Warneck JB. Buckley GM, et al. Among authors: warneck jb. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1613-5. doi: 10.1016/s0960-894x(02)00223-8. Bioorg Med Chem Lett. 2002. PMID: 12039574
8-Methoxyquinolines as PDE4 inhibitors.
Billah M, Buckley GM, Cooper N, Dyke HJ, Egan R, Ganguly A, Gowers L, Haughan AF, Kendall HJ, Lowe C, Minnicozzi M, Montana JG, Oxford J, Peake JC, Picken CL, Piwinski JJ, Naylor R, Sabin V, Shih NY, Warneck JB. Billah M, et al. Among authors: warneck jb. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1617-9. doi: 10.1016/s0960-894x(02)00224-x. Bioorg Med Chem Lett. 2002. PMID: 12039575
Synthesis and profile of SCH351591, a novel PDE4 inhibitor.
Billah M, Cooper N, Cuss F, Davenport RJ, Dyke HJ, Egan R, Ganguly A, Gowers L, Hannah DR, Haughan AF, Kendall HJ, Lowe C, Minnicozzi M, Montana JG, Naylor R, Oxford J, Peake JC, Piwinski JJ, Runcie KA, Sabin V, Sharpe A, Shih NY, Warneck JB. Billah M, et al. Among authors: warneck jb. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1621-3. doi: 10.1016/s0960-894x(02)00225-1. Bioorg Med Chem Lett. 2002. PMID: 12039576
Aryl sulfonamides as selective PDE4 inhibitors.
Montana JG, Buckley GM, Cooper N, Dyke HJ, Gowers L, Gregory JP, Hellewell PG, Kendall HJ, Lowe C, Maxey R, Miotla J, Naylor RJ, Runcie KA, Tuladhar B, Warneck JB. Montana JG, et al. Among authors: warneck jb. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2635-40. doi: 10.1016/s0960-894x(98)00491-0. Bioorg Med Chem Lett. 1998. PMID: 9873594
PDE4 inhibitors: new xanthine analogues.
Montana JG, Cooper N, Dyke HJ, Gowers L, Gregory JP, Hellewell PG, Miotla J, Morris K, Naylor R, Tuladhar B, Warneck JB. Montana JG, et al. Among authors: warneck jb. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2925-30. doi: 10.1016/s0960-894x(98)00524-1. Bioorg Med Chem Lett. 1998. PMID: 9873649
7-Methoxybenzofuran-4-carboxamides as PDE 4 inhibitors: a potential treatment for asthma.
Buckley G, Cooper N, Dyke HJ, Galleway F, Gowers L, Gregory JC, Hannah DR, Haughan AF, Hellewell PG, Kendall HJ, Lowe C, Maxey R, Montana JG, Naylor R, Picken CL, Runcie KA, Sabin V, Tuladhar BR, Warneck JB. Buckley G, et al. Among authors: warneck jb. Bioorg Med Chem Lett. 2000 Sep 18;10(18):2137-40. doi: 10.1016/s0960-894x(00)00426-1. Bioorg Med Chem Lett. 2000. PMID: 10999488
17 results