Wargent E - Search Results

1

Inhibition of insulin secretion by betagranin, an N-terminal chromogranin A fragment.

Schmid GM, Meda P, Caille D, Wargent E, O'Dowd J, Hochstrasser DF, Cawthorne MA, Sanchez JC. Schmid GM, et al. Among authors: wargent e. J Biol Chem. 2007 Apr 27;282(17):12717-24. doi: 10.1074/jbc.M700788200. Epub 2007 Feb 8. J Biol Chem. 2007. PMID: 17289672 Free article.

2

Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases.

Christiansen E, Watterson KR, Stocker CJ, Sokol E, Jenkins L, Simon K, Grundmann M, Petersen RK, Wargent ET, Hudson BD, Kostenis E, Ejsing CS, Cawthorne MA, Milligan G, Ulven T. Christiansen E, et al. Among authors: wargent et. Br J Nutr. 2015 Jun 14;113(11):1677-88. doi: 10.1017/S000711451500118X. Epub 2015 Apr 28. Br J Nutr. 2015. PMID: 25916176 Free article.

3

Prevention of diet-induced obesity and impaired glucose tolerance in rats following administration of leptin to their mothers.

Stocker CJ, Wargent E, O'Dowd J, Cornick C, Speakman JR, Arch JR, Cawthorne MA. Stocker CJ, et al. Among authors: wargent e. Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R1810-8. doi: 10.1152/ajpregu.00676.2006. Epub 2007 Jan 18. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17234956 Free article.

4

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.

Bellahcene M, O'Dowd JF, Wargent ET, Zaibi MS, Hislop DC, Ngala RA, Smith DM, Cawthorne MA, Stocker CJ, Arch JR. Bellahcene M, et al. Br J Nutr. 2013 May 28;109(10):1755-64. doi: 10.1017/S0007114512003923. Epub 2012 Oct 31. Br J Nutr. 2013. PMID: 23110765

5

Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation.

Wargent E, Sennitt MV, Stocker C, Mayes AE, Brown L, O'Dowd J, Wang S, Einerhand AW, Mohede I, Arch JR, Cawthorne MA. Wargent E, et al. Lipids Health Dis. 2005 Jan 10;4:3. doi: 10.1186/1476-511X-4-3. Lipids Health Dis. 2005. PMID: 15642120 Free PMC article.

6

Evidence from studies in rodents and in isolated adipocytes that agonists of the chemerin receptor CMKLR1 may be beneficial in the treatment of type 2 diabetes.

Wargent ET, Zaibi MS, O'Dowd JF, Cawthorne MA, Wang SJ, Arch JR, Stocker CJ. Wargent ET, et al. PeerJ. 2015 Feb 5;3:e753. doi: 10.7717/peerj.753. eCollection 2015. PeerJ. 2015. PMID: 25699203 Free PMC article.

7

Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes.

Christiansen E, Hansen SV, Urban C, Hudson BD, Wargent ET, Grundmann M, Jenkins L, Zaibi M, Stocker CJ, Ullrich S, Kostenis E, Kassack MU, Milligan G, Cawthorne MA, Ulven T. Christiansen E, et al. Among authors: wargent et. ACS Med Chem Lett. 2013 May 9;4(5):441-445. doi: 10.1021/ml4000673. Epub 2013 Apr 8. ACS Med Chem Lett. 2013. PMID: 23687558 Free PMC article.

8

Circulating levels of the cytokines IL10, IFNγ and resistin in an obese mouse model of developmental programming.

Kępczyńska MA, Wargent ET, Cawthorne MA, Arch JR, O'Dowd JF, Stocker CJ. Kępczyńska MA, et al. Among authors: wargent et. J Dev Orig Health Dis. 2013 Dec;4(6):491-8. doi: 10.1017/S2040174413000263. J Dev Orig Health Dis. 2013. PMID: 24924228

9

Identification of a novel agonist of peroxisome proliferator-activated receptors alpha and gamma that may contribute to the anti-diabetic activity of guggulipid in Lep(ob)/Lep(ob) mice.

Cornick CL, Strongitharm BH, Sassano G, Rawlins C, Mayes AE, Joseph AN, O'Dowd J, Stocker C, Wargent E, Cawthorne MA, Brown AL, Arch JR. Cornick CL, et al. Among authors: wargent e. J Nutr Biochem. 2009 Oct;20(10):806-15. doi: 10.1016/j.jnutbio.2008.07.010. Epub 2008 Oct 15. J Nutr Biochem. 2009. PMID: 18926687

10

Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy.

Hansen SV, Christiansen E, Urban C, Hudson BD, Stocker CJ, Due-Hansen ME, Wargent ET, Shimpukade B, Almeida R, Ejsing CS, Cawthorne MA, Kassack MU, Milligan G, Ulven T. Hansen SV, et al. Among authors: wargent et. J Med Chem. 2016 Mar 24;59(6):2841-6. doi: 10.1021/acs.jmedchem.5b01962. Epub 2016 Mar 15. J Med Chem. 2016. PMID: 26928019

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