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Cancer whole-genome sequencing: present and future.
Nakagawa H, Wardell CP, Furuta M, Taniguchi H, Fujimoto A. Nakagawa H, et al. Among authors: wardell cp. Oncogene. 2015 Dec 3;34(49):5943-50. doi: 10.1038/onc.2015.90. Epub 2015 Mar 30. Oncogene. 2015. PMID: 25823020 Review.
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.
Fujimoto A, Furuta M, Totoki Y, Tsunoda T, Kato M, Shiraishi Y, Tanaka H, Taniguchi H, Kawakami Y, Ueno M, Gotoh K, Ariizumi S, Wardell CP, Hayami S, Nakamura T, Aikata H, Arihiro K, Boroevich KA, Abe T, Nakano K, Maejima K, Sasaki-Oku A, Ohsawa A, Shibuya T, Nakamura H, Hama N, Hosoda F, Arai Y, Ohashi S, Urushidate T, Nagae G, Yamamoto S, Ueda H, Tatsuno K, Ojima H, Hiraoka N, Okusaka T, Kubo M, Marubashi S, Yamada T, Hirano S, Yamamoto M, Ohdan H, Shimada K, Ishikawa O, Yamaue H, Chayama K, Miyano S, Aburatani H, Shibata T, Nakagawa H. Fujimoto A, et al. Nat Genet. 2016 May;48(5):500-9. doi: 10.1038/ng.3547. Epub 2016 Apr 11. Nat Genet. 2016. PMID: 27064257
Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing.
Rasche L, Chavan SS, Stephens OW, Patel PH, Tytarenko R, Ashby C, Bauer M, Stein C, Deshpande S, Wardell C, Buzder T, Molnar G, Zangari M, van Rhee F, Thanendrarajan S, Schinke C, Epstein J, Davies FE, Walker BA, Meissner T, Barlogie B, Morgan GJ, Weinhold N. Rasche L, et al. Among authors: wardell c. Nat Commun. 2017 Aug 16;8(1):268. doi: 10.1038/s41467-017-00296-y. Nat Commun. 2017. PMID: 28814763 Free PMC article.
BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma.
Boyle EM, Ashby C, Tytarenko RG, Deshpande S, Wang H, Wang Y, Rosenthal A, Sawyer J, Tian E, Flynt E, Hoering A, Johnson SK, Rutherford MW, Wardell CP, Bauer MA, Dumontet C, Facon T, Thanendrarajan S, Schinke CD, Zangari M, van Rhee F, Barlogie B, Cairns D, Jackson G, Thakurta A, Davies FE, Morgan GJ, Walker BA. Boyle EM, et al. Among authors: wardell cp. Clin Cancer Res. 2020 May 15;26(10):2422-2432. doi: 10.1158/1078-0432.CCR-19-1507. Epub 2020 Jan 27. Clin Cancer Res. 2020. PMID: 31988198 Free article.
The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Boyle EM, Deshpande S, Tytarenko R, Ashby C, Wang Y, Bauer MA, Johnson SK, Wardell CP, Thanendrarajan S, Zangari M, Facon T, Dumontet C, Barlogie B, Arbini A, Rustad EH, Maura F, Landgren O, Zhan F, van Rhee F, Schinke C, Davies FE, Morgan GJ, Walker BA. Boyle EM, et al. Among authors: wardell cp. Nat Commun. 2021 Jan 12;12(1):293. doi: 10.1038/s41467-020-20524-2. Nat Commun. 2021. PMID: 33436579 Free PMC article.
A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma.
Reed MR, Lyle AG, De Loose A, Maddukuri L, Learned K, Beale HC, Kephart ET, Cheney A, van den Bout A, Lee MP, Hundley KN, Smith AM, DesRochers TM, Vibat CRT, Gokden M, Salama S, Wardell CP, Eoff RL, Vaske OM, Rodriguez A. Reed MR, et al. Among authors: wardell cp. Cells. 2021 Dec 2;10(12):3400. doi: 10.3390/cells10123400. Cells. 2021. PMID: 34943910 Free PMC article.
APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma.
Walker BA, Wardell CP, Murison A, Boyle EM, Begum DB, Dahir NM, Proszek PZ, Melchor L, Pawlyn C, Kaiser MF, Johnson DC, Qiang YW, Jones JR, Cairns DA, Gregory WM, Owen RG, Cook G, Drayson MT, Jackson GH, Davies FE, Morgan GJ. Walker BA, et al. Among authors: wardell cp. Nat Commun. 2015 Apr 23;6:6997. doi: 10.1038/ncomms7997. Nat Commun. 2015. PMID: 25904160 Free PMC article.
Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.
Fujimoto A, Furuta M, Totoki Y, Tsunoda T, Kato M, Shiraishi Y, Tanaka H, Taniguchi H, Kawakami Y, Ueno M, Gotoh K, Ariizumi S, Wardell CP, Hayami S, Nakamura T, Aikata H, Arihiro K, Boroevich KA, Abe T, Nakano K, Maejima K, Sasaki-Oku A, Ohsawa A, Shibuya T, Nakamura H, Hama N, Hosoda F, Arai Y, Ohashi S, Urushidate T, Nagae G, Yamamoto S, Ueda H, Tatsuno K, Ojima H, Hiraoka N, Okusaka T, Kubo M, Marubashi S, Yamada T, Hirano S, Yamamoto M, Ohdan H, Shimada K, Ishikawa O, Yamaue H, Chayama K, Miyano S, Aburatani H, Shibata T, Nakagawa H. Fujimoto A, et al. Nat Genet. 2016 May 27;48(6):700. doi: 10.1038/ng0616-700a. Nat Genet. 2016. PMID: 27230686 No abstract available.
83 results