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Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.
AbuHammad S, Cullinane C, Martin C, Bacolas Z, Ward T, Chen H, Slater A, Ardley K, Kirby L, Chan KT, Brajanovski N, Smith LK, Rao AD, Lelliott EJ, Kleinschmidt M, Vergara IA, Papenfuss AT, Lau P, Ghosh P, Haupt S, Haupt Y, Sanij E, Poortinga G, Pearson RB, Falk H, Curtis DJ, Stupple P, Devlin M, Street I, Davies MA, McArthur GA, Sheppard KE. AbuHammad S, et al. Among authors: ward t. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17990-18000. doi: 10.1073/pnas.1901323116. Epub 2019 Aug 22. Proc Natl Acad Sci U S A. 2019. PMID: 31439820 Free PMC article.
Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma.
Smith LK, Parmenter T, Kleinschmidt M, Kusnadi EP, Kang J, Martin CA, Lau P, Patel R, Lorent J, Papadopoli D, Trigos A, Ward T, Rao AD, Lelliott EJ, Sheppard KE, Goode D, Hicks RJ, Tiganis T, Simpson KJ, Larsson O, Blythe B, Cullinane C, Wickramasinghe VO, Pearson RB, McArthur GA. Smith LK, et al. Among authors: ward t. Nat Commun. 2022 Mar 1;13(1):1100. doi: 10.1038/s41467-022-28705-x. Nat Commun. 2022. PMID: 35232962 Free PMC article.
Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737.
Oakes SR, Vaillant F, Lim E, Lee L, Breslin K, Feleppa F, Deb S, Ritchie ME, Takano E, Ward T, Fox SB, Generali D, Smyth GK, Strasser A, Huang DC, Visvader JE, Lindeman GJ. Oakes SR, et al. Among authors: ward t. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2766-71. doi: 10.1073/pnas.1104778108. Epub 2011 Jul 18. Proc Natl Acad Sci U S A. 2012. PMID: 21768359 Free PMC article.
Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.
Asselin-Labat ML, Sutherland KD, Vaillant F, Gyorki DE, Wu D, Holroyd S, Breslin K, Ward T, Shi W, Bath ML, Deb S, Fox SB, Smyth GK, Lindeman GJ, Visvader JE. Asselin-Labat ML, et al. Among authors: ward t. Mol Cell Biol. 2011 Nov;31(22):4609-22. doi: 10.1128/MCB.05766-11. Epub 2011 Sep 19. Mol Cell Biol. 2011. PMID: 21930782 Free PMC article.
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.
Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, Asselin-Labat ML, Gyorki DE, Ward T, Partanen A, Feleppa F, Huschtscha LI, Thorne HJ; kConFab; Fox SB, Yan M, French JD, Brown MA, Smyth GK, Visvader JE, Lindeman GJ. Lim E, et al. Among authors: ward t. Nat Med. 2009 Aug;15(8):907-13. doi: 10.1038/nm.2000. Epub 2009 Aug 2. Nat Med. 2009. PMID: 19648928
Interfacially enhanced superconductivity in Fe(Te,Se)/Bi4Te3 heterostructures.
Chen AH, Lu Q, Hershkovitz E, Crespillo ML, Mazza AR, Smith T, Ward TZ, Eres G, Gandhi S, Mahfuz MM, Starchenko V, Hattar K, Lee JS, Kim H, Moore RG, Brahlek M. Chen AH, et al. Among authors: ward tz. Adv Mater. 2024 May 8:e2401809. doi: 10.1002/adma.202401809. Online ahead of print. Adv Mater. 2024. PMID: 38717569
Impact of long COVID on health-related quality-of-life: an OpenSAFELY population cohort study using patient-reported outcome measures (OpenPROMPT).
Carlile O, Briggs A, Henderson AD, Butler-Cole BFC, Tazare J, Tomlinson LA, Marks M, Jit M, Lin LY, Bates C, Parry J, Bacon SCJ, Dillingham I, Dennison WA, Costello RE, Walker AJ, Hulme W, Goldacre B, Mehrkar A, MacKenna B; OpenSAFELY Collaborative; Herrett E, Eggo RM. Carlile O, et al. Lancet Reg Health Eur. 2024 Apr 24;40:100908. doi: 10.1016/j.lanepe.2024.100908. eCollection 2024 May. Lancet Reg Health Eur. 2024. PMID: 38689605 Free PMC article.
1,780 results