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Repeated blood-brain barrier opening with an implantable ultrasound device for delivery of albumin-bound paclitaxel in patients with recurrent glioblastoma: a phase 1 trial.
Sonabend AM, Gould A, Amidei C, Ward R, Schmidt KA, Zhang DY, Gomez C, Bebawy JF, Liu BP, Bouchoux G, Desseaux C, Helenowski IB, Lukas RV, Dixit K, Kumthekar P, Arrieta VA, Lesniak MS, Carpentier A, Zhang H, Muzzio M, Canney M, Stupp R. Sonabend AM, et al. Among authors: ward r. Lancet Oncol. 2023 May;24(5):509-522. doi: 10.1016/S1470-2045(23)00112-2. Lancet Oncol. 2023. PMID: 37142373 Free PMC article. Clinical Trial.
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
Thomson C, Barton P, Braybrooke E, Colclough N, Dong Z, Evans L, Floc'h N, Guérot C, Hargreaves D, Khurana P, Li S, Li X, Lister A, McCoull W, McWilliams L, Orme JP, Packer MJ, Swaih AM, Ward RA, Winlow P, Ye Y. Thomson C, et al. Among authors: ward ra. J Med Chem. 2024 May 21. doi: 10.1021/acs.jmedchem.4c00227. Online ahead of print. J Med Chem. 2024. PMID: 38770784
Vinylpyridine as a Tunable Covalent Warhead Targeting C797 in EGFR.
Pemberton N, Compagne N, Argyrou A, Evertsson E, Gunnarsson A, Kettle JG, Orme JP, Ward RA. Pemberton N, et al. Among authors: ward ra. ACS Med Chem Lett. 2024 Apr 5;15(5):583-589. doi: 10.1021/acsmedchemlett.3c00425. eCollection 2024 May 9. ACS Med Chem Lett. 2024. PMID: 38746885
Parenchymal obliteration by renal masses: Functional and oncologic implications.
Kazama A, Munoz-Lopez C, Attawettayanon W, Boumitri M, Maina E, Lone Z, Rathi N, Lewis K, Campbell RA, Palacios DA, Kaouk J, Haber GP, Haywood S, Almassi N, Weight CJ, Remer EM, Ward R, Nowacki AS, Campbell SC. Kazama A, et al. Among authors: ward r. Urol Oncol. 2024 May 9:S1078-1439(24)00439-3. doi: 10.1016/j.urolonc.2024.04.019. Online ahead of print. Urol Oncol. 2024. PMID: 38729867 Free article.
BTK inhibitor-induced defects in human neutrophil effector activity against Aspergillus fumigatus are restored by TNFα.
Vargas-Blanco DA, Hepworth OW, Basham KJ, Simaku P, Crossen AJ, Timmer KD, Hopke A, Brown Harding H, Vandal SR, Jensen KN, Floyd DJ, Reedy JL, Reardon C, Mansour MK, Ward RA, Irimia D, Abramson JS, Vyas JM. Vargas-Blanco DA, et al. Among authors: ward ra. JCI Insight. 2024 May 7:e176162. doi: 10.1172/jci.insight.176162. Online ahead of print. JCI Insight. 2024. PMID: 38713531 Free article.
4,373 results