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Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma.
Yarova PL, Huang P, Schepelmann MW, Bruce R, Ecker R, Nica R, Telezhkin V, Traini D, Gomes Dos Reis L, Kidd EJ, Ford WR, Broadley KJ, Kariuki BM, Corrigan CJ, Ward JPT, Kemp PJ, Riccardi D. Yarova PL, et al. Among authors: ward jpt. J Pharmacol Exp Ther. 2021 Jan;376(1):51-63. doi: 10.1124/jpet.120.000281. Epub 2020 Oct 28. J Pharmacol Exp Ther. 2021. PMID: 33115824
Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.
Mahn K, Hirst SJ, Ying S, Holt MR, Lavender P, Ojo OO, Siew L, Simcock DE, McVicker CG, Kanabar V, Snetkov VA, O'Connor BJ, Karner C, Cousins DJ, Macedo P, Chung KF, Corrigan CJ, Ward JP, Lee TH. Mahn K, et al. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10775-80. doi: 10.1073/pnas.0902295106. Epub 2009 Jun 16. Proc Natl Acad Sci U S A. 2009. PMID: 19541629 Free PMC article.
Profiling of healthy and asthmatic airway smooth muscle cells following interleukin-1β treatment: a novel role for CCL20 in chronic mucus hypersecretion.
Faiz A, Weckmann M, Tasena H, Vermeulen CJ, Van den Berge M, Ten Hacken NHT, Halayko AJ, Ward JPT, Lee TH, Tjin G, Black JL, Haghi M, Xu CJ, King GG, Farah CS, Oliver BG, Heijink IH, Burgess JK. Faiz A, et al. Among authors: ward jpt. Eur Respir J. 2018 Aug 9;52(2):1800310. doi: 10.1183/13993003.00310-2018. Print 2018 Aug. Eur Respir J. 2018. PMID: 29946002 Free article.
67 results