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Elimination of rNMPs from mitochondrial DNA has no effect on its stability.
Wanrooij PH, Tran P, Thompson LJ, Carvalho G, Sharma S, Kreisel K, Navarrete C, Feldberg AL, Watt DL, Nilsson AK, Engqvist MKM, Clausen AR, Chabes A. Wanrooij PH, et al. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14306-14313. doi: 10.1073/pnas.1916851117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513727 Free PMC article.
Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired.
Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A. Wanrooij PH, et al. Among authors: wanrooij s. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12466-12471. doi: 10.1073/pnas.1713085114. Epub 2017 Nov 6. Proc Natl Acad Sci U S A. 2017. PMID: 29109257 Free PMC article.
Ribonucleotides in mitochondrial DNA.
Wanrooij PH, Chabes A. Wanrooij PH, et al. FEBS Lett. 2019 Jul;593(13):1554-1565. doi: 10.1002/1873-3468.13440. Epub 2019 May 24. FEBS Lett. 2019. PMID: 31093968 Free article. Review.
De novo dNTP production is essential for normal postnatal murine heart development.
Tran P, Wanrooij PH, Lorenzon P, Sharma S, Thelander L, Nilsson AK, Olofsson AK, Medini P, von Hofsten J, Stål P, Chabes A. Tran P, et al. Among authors: wanrooij ph. J Biol Chem. 2019 Nov 1;294(44):15889-15897. doi: 10.1074/jbc.RA119.009492. Epub 2019 Jul 12. J Biol Chem. 2019. PMID: 31300555 Free PMC article.
Mitochondrial DNA Instability in Mammalian Cells.
Carvalho G, Repolês BM, Mendes I, Wanrooij PH. Carvalho G, et al. Among authors: wanrooij ph. Antioxid Redox Signal. 2022 May;36(13-15):885-905. doi: 10.1089/ars.2021.0091. Epub 2021 Jul 2. Antioxid Redox Signal. 2022. PMID: 34015960 Free PMC article. Review.
21 results