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A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.
Fujita K, Nakamura Y, Oka T, Ito H, Tamura T, Tagawa K, Sasabe T, Katsuta A, Motoki K, Shiwaku H, Sone M, Yoshida C, Katsuno M, Eishi Y, Murata M, Taylor JP, Wanker EE, Kono K, Tashiro S, Sobue G, La Spada AR, Okazawa H. Fujita K, et al. Among authors: wanker ee. Nat Commun. 2013;4:1816. doi: 10.1038/ncomms2828. Nat Commun. 2013. PMID: 23652004 Free PMC article.
Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays.
Grelle G, Kostka S, Otto A, Kersten B, Genser KF, Müller EC, Wälter S, Böddrich A, Stelzl U, Hänig C, Volkmer-Engert R, Landgraf C, Alberti S, Höhfeld J, Strödicke M, Wanker EE. Grelle G, et al. Among authors: wanker ee. Mol Cell Proteomics. 2006 Feb;5(2):234-44. doi: 10.1074/mcp.M500198-MCP200. Epub 2005 Nov 7. Mol Cell Proteomics. 2006. PMID: 16275660 Free article.
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
Hoshino M, Qi ML, Yoshimura N, Miyashita T, Tagawa K, Wada Y, Enokido Y, Marubuchi S, Harjes P, Arai N, Oyanagi K, Blandino G, Sudol M, Rich T, Kanazawa I, Wanker EE, Saitoe M, Okazawa H. Hoshino M, et al. Among authors: wanker ee. J Cell Biol. 2006 Feb 13;172(4):589-604. doi: 10.1083/jcb.200509132. Epub 2006 Feb 6. J Cell Biol. 2006. PMID: 16461361 Free PMC article.
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
Boeddrich A, Gaumer S, Haacke A, Tzvetkov N, Albrecht M, Evert BO, Müller EC, Lurz R, Breuer P, Schugardt N, Plassmann S, Xu K, Warrick JM, Suopanki J, Wüllner U, Frank R, Hartl UF, Bonini NM, Wanker EE. Boeddrich A, et al. Among authors: wanker ee. EMBO J. 2006 Apr 5;25(7):1547-58. doi: 10.1038/sj.emboj.7601043. Epub 2006 Mar 9. EMBO J. 2006. PMID: 16525503 Free PMC article.
196 results